Memory Flashcards

1
Q

What are the three stages of learning and memory?

A
  1. Encoding of information into memory
  2. Storage of information within memory system
  3. Retrieval of stored information from memory
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2
Q

What are the features of the multi-store model of memory?

A
  1. Modality-specific sensory stores
  2. Short-term store of very limited capacity
  3. Long-term store of unlimited capacity
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3
Q

What is the iconic store?

A

Brief sensory store for visual information

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4
Q

How quickly does information in the iconic store decay?

A

In less than a second

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5
Q

What is the echoic store?

A

Brief sensory store for auditory information

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6
Q

How quickly does information in the echoic store decay?

A

Two seconds

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7
Q

What is the capacity of short-term memory?

A

~7 integrated units of information

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8
Q

How can information be retained in short-term memory?

A

Rehearsal

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9
Q

What is the recency effect?

A

The last few items in a list are more likely to be recalled because they are still in short-term memory

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10
Q

What is the cause of short-term memory forgetting?

A

Interference

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11
Q

What is the primacy effect?

A

The first few items in a list are more likely to be recalled because they have moved to long-term memory

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12
Q

What are the criticisms of the multi-store model?

A
  1. Assumes that short-term memory processing is necessary for encoding into long-term memory
  2. Assumes that only amount of rehearsal correlates with conversion of short-term memory to long-term memory
  3. Assumes that each store only operates in a single unitary way
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13
Q

What are the four primary components of the working memory model?

A
  1. Phonological loop
  2. Visuospatial sketchpad
  3. Multimodal episodic buffer
  4. Modality-free central executive
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14
Q

What is the role of the central executive?

A

Selects and initiates cognitive processing routines

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15
Q

What is the standard forgetting curve?

A

Retention decreases as retention interval increases, but rate of forgetting slows down

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16
Q

What is the consolidation period?

A

Period of time during which new memories are vulnerable but are being strengthened

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17
Q

What are the factors that influence how a permanent representation of information is encoded and stored?

A
  1. Practice
  2. Level of processing
  3. Organisation
  4. Spacing
  5. Active retrieval
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18
Q

How does practice improve retrieval?

A

Improves accuracy to 100%

Following perfect recall, practice decreases retrieval time

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19
Q

How does level of processing affect recall?

A

Greater depth of processing creates more richly encoded or elaborate memory representation

Semantic processing and self-generation provide subject with richer and more elaborate code, which yields additional retrieval routes

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20
Q

How does organisation affect retrieval?

A

A mechanism for cueing the memory of individual items improves memory

More systematic way of going through memory and retrieving information

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21
Q

How does spacing affect retrieval?

A

Memory is better for repeated information if it is spaced out over time rather than lumped together

For long-term retention, spaced out study is better

For short-term retention, massed study is better (cramming)

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22
Q

What is active retrieval?

A

Practising retrieval whilst studying

More powerful learning activity than active encoding

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23
Q

What is transfer-appropriate processing?

A

Principle that retrieval is more likely if cues available at recall are the same as those present during encoding

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24
Q

What are schemas?

A

Knowledge structures that we build upon to store new facts and use to reconstruct memories

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25
What is retrograde amnesia?
Forgetting of events prior to the trauma Gradient of forgetting diminishes with more remote memories and may recover with time
26
What is anterograde amnesia?
Inability to retain new information and build new memories Inability to learn
27
What are the features of medial temporal lobe amnesia?
1. Profound, polymodal anterograde amnesia for verbal and non-verbal material 2. Severe recognition memory deficit 3. Mild retrograde amnesia 4. Intact digit and spatial span (short-term memory) 5. Preserved IQ
28
What is the result of a unilateral right medial temporal lobe lesion?
Non-verbal memory deficit
29
What is the result of a unilateral left medial temporal lobe lesion?
Verbal memory deficit
30
What are the features of diencephalic amnesia?
Anterograde amnesia Includes damage to mediodorsal nucleus of thalamus and Korsakoff's syndrome
31
What is associative agnosia?
Patient cannot recognise objects, name them or use them correctly but can identify them by selecting the correct drawing and can draw them accurately
32
What is apperceptive agnosia?
Patient can name the object but cannot draw it Cannot name the object if it is presented in an unusual way
33
What is declarative memory?
Explicit memory Memory of facts (semantic) and events (episodic)
34
What is procedural memory?
Implicit memory Memory of skills Learn through performance Includes classical conditioning
35
Which brain structures might procedural memory involve?
1. Basal ganglia | 2. Cerebellum
36
What does the delayed non-matching to sample task test?
Recognition memory
37
What does the lifesaver motor skill task test?
Skill learning
38
What kind of cortical damage are impairments to recognition memory associated with?
Damage to rhinal cortex within the medial temporal lobe
39
Which cortical projections are crucial for visual recognition memory?
Projections from inferotemporal cortex to rhinal cortex
40
What does damage to the amygdala affect?
Affective/motivational/emotional memory Loss of fear conditioning
41
What is the allocortex?
Primitive cortex Hippocampus and dentate gyrus
42
What lies between the allocortex and the neocortex?
1. Subiculum 2. Parahippocampal cortex also primitive cortex, some is transitional
43
How many layers does allocortex have?
3
44
How many layers does transitional cortex have?
4-5
45
What is the hippocampus proper divided into?
Three longitudinal layers CA1, CA2 and CA3
46
What do the CA areas consist of?
Pyramidal output cells
47
What does the dentate gyrus consist of?
Granule input cells
48
What are the three main classes of afferent connections to the hippocampus?
1. All major cortical association areas 2. Subcortical structures 3. Non-specific arousal systems
49
Where do cortical association areas project to?
Entorhinal cortex
50
Where does the entorhinal cortex send afferents to?
Dentate gyrus granule cells
51
What is the perforant pathway?
Afferents from entorhinal cortex to dentate gyrus granule cells because these fibres are said to perforate hippocampal fissure in reaching their destination
52
What does the perforant pathway synapse onto?
1. Granule cells | 2. Apical dendrites of CA3 pyramidal cells
53
How do the CA3 cells project to CA1 cells?
Via Schaffer collaterals
54
What do the CA1 cells project to?
The subiculum
55
What are the two major sets of hippocampal efferent connections?
1. Projections from subiculum and entorhinal cortex to neocortex 2. Projections from CA3 and subiculum through the fimbria-fornix to structures such as the hypothalamus, mammillary bodies, anterior thalamus and nucleus accumbens
56
What is Papez circuit?
1. Hippocampus 2. Mammillary body 3. Thalamus 4. Cingulate cortex 5. Hippocampus
57
How do dentate gyrus granule cells project onto CA3 cells?
Mossy fibres
58
What is the effect of CA1 cell degeneration?
Loss of episodic memory
59
Which brain structure is important for spatial memory?
Hippocampus
60
What does the Morris Water Maze test?
Spatial memory
61
What type of memory is navigational memory?
Episodic memory Spatial memory
62
How is learning influenced in the hippocampus?
Unsupervised learning system General state may influence level and/or rate of learning via non-specific arousal pathways Back-projections to neocortex
63
What are the five properties of long-term potentiation that make it a useful synaptic model for learning and memory?
1. Rapidly induced 2. Long-lasting 3. Synapse specific 4. Associative in nature (CA1 only) 5. Also seen in neocortex
64
Which neurotransmitter is used in the hippocampus?
Glutamate (excitatory)
65
What are the three types of glutamate receptor?
1. Quisqualate 2. Kainate 3. NMDA
66
Which glutamate receptors mediate normal fast transmission?
Quisqualate and kainate
67
What is the effect of specific activation of NMDA receptors?
No effect
68
What is AP5?
Specific NMDA antagonist
69
What is the effect of AP5?
Blocks LTP development in CA3-CA1 pathway
70
What are NMDA receptors involved in?
LTP and spatial learning