Membrane Transport Flashcards

1
Q

Types of Membrane Transport

A

Passive Diffusion
Active Diffusion
Vesicular

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2
Q

Which types of membrane transport DON’T require energy

A

Passive DIffusion

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3
Q

What types of membrane transport DO require energy

A

Active Transport

Vesicular

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4
Q

Types of Passive Diffusion

A

Through membrane
Through channels
Facilitated Diffusion

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5
Q

What can be transported through membrane

A

gases

small uncharged molecules

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6
Q

What type of transporter does facilitated diffusion use

A

uniporter

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7
Q

uniporter

A

carries 1 substance down it’s concentration gradient

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8
Q

What does facilitated diffusion transport

A

single type of molecule

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9
Q

What’s an example of a problem that can happen with facilitated diffusion

A

Type I diabetes

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10
Q

What are factors that affect passive diffusion through channels

A

permeability
concentration gradient
selectivity

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11
Q

Types of passive diffusion channels

A

Water

Ions

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12
Q

What are water channels mediated by

A

aquaporins

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13
Q

What is an example of a problem caused with mutated aquaporins

A

ND1

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14
Q

Ion Channels have what kind of movement

A

down electrchemical gradient

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15
Q

What are different types of gates

A

Mechanical, Ligand, Voltage

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16
Q

Primary Active transport

A

Pumps driven directly by ATPase

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17
Q

How does primary active transport transport small uncharged molecules

A

against their concentration gradient

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18
Q

How does primary active transport transport ions

A

against their electrochemical graident

19
Q

What type of transporters does secondary active transport use

A

antiport, symport

20
Q

Secondary active transport

A

pumps driven indirectly by ATPase

21
Q

Antiporter

A

transports two substances in opposite directions

22
Q

Symporter

A

transports two substances in the same direction

23
Q

What is an ABC transporter an example of

A

primary active transport

24
Q

What does ABC protein/transporter mean

A

ATP binding cassette

25
Q

What are some functions of ABC proteins

A

hydrolyze ATP
act as ion channel
regulate ion channels

26
Q

What is an example of an ABC protein

A

CFTR, MDR

27
Q

What does vesicular transport involve

A

lipid fusion

28
Q

What are examples of vesicular transport

A

exocytosis

endocytosis

29
Q

What is the function of vesicular transport

A

to deal with larger molecules

30
Q

What are examples of endocytosis

A

phagocytosis

pinocytosis

31
Q

phagocytosis

A

engulfing solid particule

32
Q

examples of pinocytosis

A

fluid phase
caveolae
receptor mediated

33
Q

What is an example of receptor mediated pinocytosis

A

clathrin-mediated

34
Q

What does clathrin mediated pinocytosis do

A

forms a big net

35
Q

Exocytosis

A

material gets packaged into vesicles, which are then extreted to the ECM

36
Q

What is an example of a problem that can happen with vesicular transport

A

familial hypercholstermia

37
Q

Familial hypercholestermia puts you at a higher risk for what

A

atherosclerosis

coronary heart disease

38
Q

Familial hypercholestermia has high plasma levels of _____

A

LDL cholesterol

39
Q

NDI is caused by what

A

mutation in aquaporin-2 gene

40
Q

symptoms of NDI

A

excrete large amounts of diluted urine

excessive thirst

41
Q

characteristics of facilitated diffusion through uniporter

A

transport rate is higher than simmple diffusion
its reversible
its specific

42
Q

Vmax

A

max transport rate

43
Q

what are factors that control the transport rate

A

conc gradient
transporter number
affinity of binding

44
Q

how is glucose conc gradient maintained

A

converting glucose to glucose-6-phosphate