Autonomic Nervous System III Flashcards

1
Q

Homotropic interactions

A

transmitter inhibits the nerve terminal that it’s being released from

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2
Q

What type of receptor has homotropic interactions

A

M2 or alpha2

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3
Q

Heterotropic interactiosn

A

one neurotransmitter affects the release of another via actions of heteroreceptors

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4
Q

What type of receptor has heterotropic interactions

A

alpha2

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5
Q

Denervation supersentitivity

A

i. Basically you have like beta blockers that are blocking ganglionic transmission, then you take it away and target organs become supersensitive

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6
Q

Mechanisms of denervation supersentivity

A
  1. Proliferation of receptors

2. Loss of mechanisms for removal of transmitter

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7
Q

Cotransmission

A

neurons release more than 1 transmitter or modulator

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8
Q

Fnctions of autonomic nervous system

A

help body maintain constant internal environment

accommodate coordinated responses to external stimuli

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9
Q

Are the sympathetic and parasymphatic nervous systems physiologicalopposites?

A

NO

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10
Q

what neurotransmitters have autoreceptors

A

NE and AcH

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11
Q

what are sympathetic autoreceptors

A

alpha-2

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12
Q

what are parasympathetic autoreceptors

A

M2

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13
Q

activation of autoreceptors causes what

A

inhibition of release of their subtance

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14
Q

binding of NE to parasympathetic nervce can do whatq

A

decrease secretion of acetylcholine

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15
Q

acetylcholine released to sympathetic nerve receptors can do waht

A

decrease release of EN

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16
Q

heteroreceptors on sympaethtic nerves are M2 receptors that do what

A

respond to ACh to decrease cAMP

17
Q

heteroreceptors on parasympathetic nerves are A2 receptors that do waht

A

repond to norepinephrine

18
Q

neuromodulator

A

substance/hormone peptide released that affects the release of another neurotransmitter

19
Q

ATP adn NE when released by small granular vesicles do what

A

act on receptors to increase Ca++ and cause contraction

20
Q

what secretes neuropeptide Y (NPY)

A

large granular vesicles

21
Q

function of NPY

A

act on receptors on target organ to cause contraction. At the same time it decreases secretion of other 2 substances

22
Q

incraeses BP has what affect on baroreceptor discharge

A

increases

23
Q

increase in baroreceptor charge does waht

A

activate vasomotor center to inhibit sympaethtic derive to decrease vasoconstriction

24
Q

decrease in bp has what affect on the kidney

A

decreases renal blood flow, increases renin production and angiotensis