Autonomic Nervous System III Flashcards
Homotropic interactions
transmitter inhibits the nerve terminal that it’s being released from
What type of receptor has homotropic interactions
M2 or alpha2
Heterotropic interactiosn
one neurotransmitter affects the release of another via actions of heteroreceptors
What type of receptor has heterotropic interactions
alpha2
Denervation supersentitivity
i. Basically you have like beta blockers that are blocking ganglionic transmission, then you take it away and target organs become supersensitive
Mechanisms of denervation supersentivity
- Proliferation of receptors
2. Loss of mechanisms for removal of transmitter
Cotransmission
neurons release more than 1 transmitter or modulator
Fnctions of autonomic nervous system
help body maintain constant internal environment
accommodate coordinated responses to external stimuli
Are the sympathetic and parasymphatic nervous systems physiologicalopposites?
NO
what neurotransmitters have autoreceptors
NE and AcH
what are sympathetic autoreceptors
alpha-2
what are parasympathetic autoreceptors
M2
activation of autoreceptors causes what
inhibition of release of their subtance
binding of NE to parasympathetic nervce can do whatq
decrease secretion of acetylcholine
acetylcholine released to sympathetic nerve receptors can do waht
decrease release of EN