Membrane Transport Flashcards

1
Q

What is passive diffusion

A

Movement of molecules directly through membrane down the conc gradient

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2
Q

What is aqueous diffusion

A

Movement of molecules down conc gradient via a channel

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3
Q

What is facilitated diffusion

A

Movement of molecules across membrane via carrier protein
Requires a conc gradient

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4
Q

Why are carrier proteins required in facilitated diffusion

A

because molecules are charged or polar, they can’t cross the phospholipid part of the membrane without help.

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5
Q

What is the role of aquaporins

A

Channel proteins that allow movement of water

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6
Q

What is active transport

A

Movement of molecules against concentration gradient requires energy via ATP hydrolysis

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7
Q

What type of diffusion is non-coupled transport

A

Passive and aqueous

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8
Q

Which GLUT is responsible for insulin secretion in pancreatic beta cells

A

GLUT1

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9
Q

What type of transporters are members of the SLC2

A

GLUT

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10
Q

What type of transport is SGLT1 a example of

A

Secondary active transport

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11
Q

The Na/K ATPase pump is an example of which type of transport

A

Primary active transport

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12
Q

In the Na/K ATPase pump ___ Na ions move ____ cell and ____ K ions move ____ cell

A

3 out
2 in

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13
Q

What is secondary active transport

A

Movement of ions against concentration gradient requires gradient by coupling

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14
Q

Which ion drives secondary active transport

A

Na

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15
Q

What does digoxin inhibit

A

Na/K ATPase pump is an

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16
Q

Digoxin inhibits Na/K ATPase pump so there is a _____ in intracellular Na and Ca

A

Rise

17
Q

What type of transport is P-glycoprotein an example of

A

Primary active transport that transports drugs

18
Q

Give an example of a anti port secondary active transport system

A

Na Ca exchanger

19
Q

Give an example of a secondary active transport symport system

A

SGLT => Na movement drives glucose movement

20
Q

During postpandrial Na absorption in jejunum what transport is involved

A

SGLT
Na/amino acid
GLUT2
Na/K ATPase pump is an

21
Q

What is NHE

A

Sodium hydrogen exchanger

22
Q

Which membrane does NHE3 work at

A

Apical

23
Q

What membrane does NHE1 work at

A

basolateral

24
Q

Which type of exchange happens in ileum and proximal colon

A

NHE and Cl/HCO3

25
Q

Name a chloride channel

A

CIC2

26
Q

Name a chloride channel

A

CIC2