voltage gated ion channels Flashcards
what does it mean by equilibrium potential
the chemical and electrical gradients are equal and opposite in direction.
concentration gradient of potassium generates a _____________
efflux
electrical gradient of potassium generates a _____________
influx
increased extracellular K ____________ membrane potential
depolarises
what is the role of astrocyte
buffer potassium
What is the resting potential of a typical neuron?
-70mV
at rest the membrane is much more permeable to
potassium
what is the equilibrium potential for K
-90mV
what is the equilibrium potential for Na
+60mV
which ion allows for depolarising phase
sodium
depolarisation cause the cell to become more ?
positive
changes to membrane potential opens ?
voltage gated channels
how is gating regulated
protein conformation
what is modulation
altering the rate of a channel gating or membrane potential at which gating occurs
what type of amino acids are responsive to increase in intracellular membrane voltage
positively charged amino acids
