Gap Junctions Flashcards
What is a gap junction
Connections between adjacent cells
What makes up a Connexon
6 connexin proteins
In which types of tissues are gap junctions commonly found?
Cardiac muscle smooth muscle and neurons
Why are gap junctions important
Allow fast direct communication and allows cells to synch activities
What does electrophysiology measure
Electrical coupling between cells
How does immunohistochemistry contribute to the study of gap junctions?
Uses antibodies to detect specific connexin proteins
What is the primary mechanism of communication in electrical synapses?
Direct ion flow through gap junctions
How do chemical synapses transmit signals?
Through release of neurotransmitters from pre synaptic neuron
What is the typical speed of signal transmission in electrical synapses compared to chemical synapses?
Electrical synapses are fast and chemical synapses are slower due to neurotransmitter release and receptor binding
Which type of synapse allows for bidirectional communication?
Electrical synapses
Which type of synapse allows for bidirectional communication?
Electrical synapses
In terms of plasticity, how do electrical synapses compare to chemical synapses?
Chemical synapses have greater plasticity allowing for hangers in strength and modulation of synaptic transmission
Which type of synapse is more common in the nervous system?
Chemical
How do electrical synapses contribute to network synchronization?
Allowing simultaneous activity across interconnected cells
What is the advantage of bidirectional communication in electrical synapses?
Coordinated activity and synchronous neuronal firing
