Membrane Physiology: Chapter 3 Flashcards

1
Q

What are the 3 types of membranes?

A

Freely permeable membrane
Selectively permeable membrane
Impermeable membrane

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2
Q

What is the purpose of plasma membrane?

A

Separation
Regulation
Communication
Structural

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3
Q

How do different molecules move across the membrane?

A

Chemical
Size
Need

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4
Q

What type of layer is the plasma membrane?

A

Phospholipid bilayer

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5
Q

What are the functional classes of membrane proteins?

A

Anchoring proteins
Recognition proteins
Enzymes
Receptor proteins
Carrier proteins
Channels

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6
Q

What are the two components of plasma membrane?

A

Integral: transport proteins
Peripheral: enzymes, cell-to-cell links

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7
Q

Can integral membrane proteins signal cascade?

A

Yes; extracellular signaling molecules bind receptors and elicit intracellular responses

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8
Q

What are the roles of membrane receptors?

A

Contact signaling: touching and recognition of cells
Chemical signaling: interaction between receptors and ligands to alter the activity of cell proteins
G protein-linked receptors: release of internal second messenger

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9
Q

What happens when contact signaling is lost?

A

Tumors occur

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10
Q

What are g protein coupled receptors? What do they do?

A

Convert extracellular signals to intracellular responses
Ligand - receptor - g protein - enzyme - 2nd messenger

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11
Q

What is glycocalyx? What is it’s function?

A

Extracellular glycoprotein
Protection - layers for recognition

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12
Q

What does cholesterol help with?

A

Determining fluidity in membrane

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13
Q

Are lipid rafts localized?

A

No; stable platforms for cell-signaling molecules (cascade triggered)

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14
Q

What determines whether a substance can passible permeate a membrane?

A

Concentration gradient
Lipid solubility of a substance
Channels of appropriate size
Carrier proteins

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15
Q

Explain simple diffusion

A

Directly through membrane without channel or carriers

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16
Q

What is facilitated diffusion?

A

Use carrier proteins that exhibit specificity, are saturable and can be regulated in terms of activity and quantity

17
Q

What is carrier mediated facilitated diffusion?

A

Diffusion via proteins carriers specific for one chemical; binding substances causing shape change

18
Q

What is channel mediated facilitated diffusion? What are 2 types?

A

Doesn’t change shape
Mostly ions are selected on basis of size and charge
Leaky, gated

19
Q

What determines diffusion rate for leaky channels?

A

Concentration rate

20
Q

What determines diffusion rate for chemically gated channels?

A

Neurotransmitters

21
Q

What determines diffusion rate for voltage gated channels?

A

Charge in and out of membrane determines if it’s open or closed

22
Q

What determines diffusion rate for mechanically gated channels?

A

Distortion

23
Q

Where does water go during osmosis?

A

Water goes toward solute, balance

24
Q

What is osmotic flow?

A

Movement fo water driven by osmosis

25
Q

What is osmotic pressure?

A

Indication of force of pure water moving into a solution with higher solute concentration

26
Q

How do the capillaries relate to hydrostatic pressure?

A

Force out water of capillary beds with high osmosis pressure

27
Q

How do osmotic and hydrostatic pressure differ?

A

Inversely related
Hydrostatic pressure decreases and osmotic pressure increases within capillaries

28
Q

What is primary active transport?

A

Molecules being pumped against concentration gradient with ATP cost

29
Q

What is secondary active transport?

A

Transport is driven by the energy stored in the concentration gradient of another molecule

30
Q

Describe sodium potassium transport

A

Inside: DNA, proteins (negative charge); +1 charge net movement
More positive is removed than what is returned
Outside: Positive

31
Q

What are the 3 types of secondary active transport?

A

Uniporter: 1 in
Symporter: 2 in
Antiporter: 1 in, 1 out