Melanoma Flashcards

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1
Q

How is melanoma identified

A

ABCDE - If any lesion has any of these features, it should be referred urgently under the 2-week wait pathway for suspected malignant melanoma:

Asymmetry
Border irregularity (melanoma often has a ‘scalloped’ border)
Colour variation (a variegated lesion is one that consists of many colours)
Diameter >6mm
Evolves over time

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2
Q

What are the four types of melanoma

A

Superficial spreading Nodular Lentigo maligna Acral lentiginous

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3
Q

What is the most common form

A

Superficial spreading

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4
Q

Where does superficial effect and what it looks like

A

Arms, legs, back and chest, young people - growing moles with diagnostic features

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5
Q

What is nodular

A

Red or black lump or lump which bleeds or oozes - most lethal

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6
Q

What does nodular effect

A

Sun exposed skin, middle-aged people

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7
Q

What is lentigo maligna

A

A growing mole with diagnostic features caused by sun exposed skin

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8
Q

Where does sacral lentigious effect

A

Nails, palms or soles, People with darker skin pigmentation

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9
Q

How doe sacral lentigious look

A

Subungual pigmentation (Hutchinson’s sign) or on palms or feet

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10
Q

What is Hutchinson’s sign

A

Hutchinson’s sign is a herpes zoster vesicle present on the tip or side of the nose. It reflects zoster involvement of the 1st branch of the trigeminal nerve, and is concerning for herpes zoster ophthalmicus.

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11
Q

What are the major diagnostic features

A

Change in size
Change in shape
Change in colour

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12
Q

What are the secondary features

A

Diameter >= 7mm
Inflammation
Oozing or bleeding
Altered sensation

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13
Q

How should suspicious lesions be treated

A

undergo excision biopsy. The lesion should be removed in completely as incision biopsy can make subsequent histopathological assessment difficult.

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14
Q

What should be done after excision diagnosis is confirmed

A

Once the diagnosis is confirmed the pathology report should be reviewed to determine whether further re-excision of margins is required

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15
Q

margins for Lesions 0-1mm thick

A

1cm

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16
Q

1-2mm lesion margins

A

1- 2cm (Depending upon site and pathological features)

17
Q

2-4mm thick lesion margins

A

2-3 cm (Depending upon site and pathological features)

18
Q

> 4mm thick lesion margins

A

3com

19
Q

What further treatments can you do

A

Further treatments such as sentinel lymph node mapping, isolated limb perfusion and block dissection of regional lymph node groups should be selectively applied.

19
Q

What further treatments can you do

A

Further treatments such as sentinel lymph node mapping, isolated limb perfusion and block dissection of regional lymph node groups should be selectively applied.