Erythema multiform Flashcards
What is eythema multiforme
Erythema multiforme is a hypersensitivity reaction that is most commonly triggered by infections. It may be divided into minor and major forms.
What is seen on inspection
target lesions
initially seen on the back of the hands / feet before spreading to the torso
upper limbs are more commonly affected than the lower limbs
pruritus is occasionally seen and is usually mild
What are the causes
Viral, idiopathic, bacterial, drugs, Connective tissue diseases, sarcoidosis, malignancy
What are the viral causes
herpes simplex virus (the most common cause), Orf*
idiopathic
What are the bacterial causes
Mycoplasma, Streptococcus
What are the drug causes
penicillin, sulphonamides, carbamazepine, allopurinol, NSAIDs, oral contraceptive pill, nevirapine
What is erythema major multiforme
The more severe form, erythema multiforme major is associated with mucosal involvement.
