cellulitis Flashcards

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1
Q

What is it

A

Cellulitis is a bacterial soft tissue infection of the dermis and subcutaneous tissue.

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2
Q

What are the risk factors

A

Advancing age
Immunocompromised e.g. diabetic
Predisposing skin condition e.g. ulcers, pressure sores, trauma, lymphoedema

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3
Q

What are the clinical features

A

Erythema
Calor (heat)
Swelling
Pain
Poorly demarcated margins
Systemic upset: fever, malaise
Lymphadenopathy
Often evidence of breach of skin barrier e.g. trauma, ulcer etc

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4
Q

What is the cause

A

Generally caused by Streptococcus and/or Staphylococcus organisms.

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5
Q

What is the management

A

Cellulitis: flucloxacillin + benzylpenicillin if severe, flucloxacillin alone if mild-moderate. Clarithromycin or clindamycin substituted if penicillin allergic.§

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5
Q

What is the management

A

Cellulitis: flucloxacillin + benzylpenicillin if severe, flucloxacillin alone if mild-moderate. Clarithromycin or clindamycin substituted if penicillin allergic.§

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6
Q

Where does it commonly occur

A

commonly occurs on the shins
erythema, pain, swelling
there may be some associated systemic upset such as fever

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7
Q

How do the investigations go

A

The diagnosis of cellulitis is clinical. No further investigations are required in primary care. Bloods and blood cultures may be requested if the patient is admitted and septicaemia is suspected.

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8
Q

What is the criteria for admission

A

ERON classification

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9
Q

What is class I

A

There are no signs of systemic toxicity and the person has no uncontrolled co-morbidities

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10
Q

What is class II

A

The person is either systemically unwell or systemically well but with a co-morbidity (for example peripheral arterial disease, chronic venous insufficiency, or morbid obesity) which may complicate or delay resolution of infection

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11
Q

What is Class III

A

The person has significant systemic upset such as acute confusion, tachycardia, tachypnoea, hypotension, or unstable co-morbidities that may interfere with a response to treatment, or a limb-threatening infection due to vascular compromize

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12
Q

What is class IV

A

The person has sepsis syndrome or a severe life-threatening infection such as necrotizing fasciitis

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13
Q

When should we admit for IV abx

A

When patient is iron class III or IV
Has severe or rapidly deteriorating cellulitis (for example extensive areas of skin).
Is very young (under 1 year of age) or frail.
Is immunocompromized.
Has significant lymphoedema.
Has facial cellulitis (unless very mild) or periorbital cellulitis.

else treat with oral abx

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14
Q

When is erythromycin used

A

To treat women in pregnancy

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15
Q

How to treat severe cellulitis

A

Offer co-amoxiclav, cefuroxime, clindamycin or ceftriaxone.

16
Q

What is orbital cellulitis

A

Orbital cellulitis is the result of an infection affecting the fat and muscles posterior to the orbital septum, within the orbit but not involving the globe. It is usually caused by a spreading upper respiratory tract infection from the sinuses and carries a high mortality rate.

17
Q

What is periorbital/preseptal cellulitis

A

less serious superficial infection anterior to the orbital septum, resulting from a superficial tissue injury (chalazion, insect bite etc…). Periorbital cellulitis can progress to orbital cellulitis.

18
Q

What are the risk factors of orbital cellulitis

A

Childhood
Mean age of hospitalisation 7-12 years
Previous sinus infection
Lack of Haemophilus influenzae type b (Hib) vaccination
Recent eyelid infection/ insect bite on eyelid (periorbital cellulitis)
Ear or facial infection

19
Q

What is the difference between orbital and preseptal

A

reduced visual acuity, proptosis, ophthalmoplegia/pain with eye movements are NOT consistent with preseptal cellulitis§

20
Q

What are we looking for in a FBC

A

WBC elevated, raised inflammatory markers

21
Q

What are we looking for in a clinical examination

A

Decreased vision, afferent pupillary defect, proptosis, dysmotility, oedema, erythema.

22
Q

What are we looking for in a CT with contrast

A

Inflammation of the orbital tissues deep to the septum, sinusitis.

23
Q

What will the blood culture show

A

Blood culture and microbiological swab to determine the organism. Most common bacterial causes – Streptococcus, Staphylococcus aureus, Haemophilus influenzae B.

24
Q

Treatment for orbital cellulitis

A

Admission + IV abx

25
Q

What is pre septal cellulitis

A

periorbital cellulitis. It is an infection of the soft tissues anterior to the orbital septum - this includes the eyelids, skin and subcutaneous tissue of the face, but not the contents of the orbit.

26
Q

What is the epidemiology of preseptal

A

Preseptal cellulitis occurs most commonly in children - 80% of patients are under 10 and the median age of presentation is 21 months
It is more common in the winter due to the increased prevalence of respiratory tract infections.

27
Q

What are the symptoms of pre septal

A

The patient presents with a red, swollen, painful eye of acute onset. They are likely to have symptoms associated with fever.

28
Q

What are the signs of preseptal

A

Erythema and oedema of the eyelids, which can spread onto the surrounding skin
Partial or complete ptosis of the eye due to swelling

29
Q

What must be absent in preseptal

A

Orbital signs (pain on movement of the eye, restriction of eye movements, proptosis, visual disturbance, chemosis, RAPD) must be absent in preseptal cellulitis - their presence would indicate orbital cellulitis

30
Q

What investigations are involved in preseptal

A

Bloods - raised inflammatory markers
Swab of any discharge present
Contrast CT of the orbit may help to differentiate between preseptal and orbital cellulitis. It should be performed in all patients suspected to have orbital cellulitis

31
Q

What is the management of pre septal

A

all cases should be referred to secondary care for assessment
Oral antibiotics are frequently sufficient - usually co-amoxiclav
Children may require admission for observation

32
Q

What are the complications in pre septal

A

Bacterial infection may spread into the orbit and evolve into orbital cellulitis