Melanocytic Lesions Pt 2 Flashcards

1
Q

What are the highest risk sites for melanoma?

A

BANS

Back, arms, neck, scalp

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2
Q

What are the ABCDE’s clinical features of melanoma?

A
Asymmetry
Border irregularity
Color variegation
Diameter greater than 6mm
Evolving - enlarging/changing in color
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3
Q

How does melanoma grow?

A

Lateral and deep into the connective tissue

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4
Q

What are the four forms of melanoma lesions?

A
  1. Lentigo maligna melanoma
  2. Superficial spreading melanoma
  3. Nodular melanoma
  4. Acral lentiginous melanoma
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5
Q

What characterizes Lentigo maligna (Hutchinson’s freckle) as melanoma in-situ?

A

Melanoma in a purely radial growth phase

Large, flat, irregular borders, uneven color

*precursor to melanoma

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6
Q

How long does it typically take a lentigo maligna to begin vertical growth, turning into a lentigo maligna melanoma?

A

~15 years

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7
Q

What is the most common type of melanoma?

A

Superficial spreading melanoma (70%)

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8
Q

T/F: Melanomas will not have hair.

A

False

They can have hair

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9
Q

Which melanoma presents as rapidly entering the vertical growth phase?

A

Nodular melanoma

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10
Q

What does it mean if a nodular melanoma is amelanotic?

A

Melanocytes so poorly differentiated they are not producing melanin

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11
Q

T/F: Nodular melanomas are more deeply pigmented than other melanoma types.

A

True

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12
Q

_____________ are most commonly found in the oral cavity, on persons of color, and are more aggressive than cutaneous melanomas.

A

Acral lentiginous

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13
Q

Where are acral lentiginous melanomas most commonly found?

A

Palm of hand, sole of feet, subungual (under nails), mucous membranes (orally)

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14
Q

Who is most at risk for oral acral lentiginous melanoma?

A

Men in 5th-7th decade

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15
Q

What are the most common sites for oral acral lentiginous melanoma?

A

Hard palate/maxillary alveolar mucosa

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16
Q

What is the treatment for melanoma?

A

Surgical excision 1-2 cm margin for cutaneous lesions -> immunotherapy

17
Q

T/F: Chemotherapy and radiation are very effective against melanoma.

A

False

18
Q

T/F: Melanomas on the trunk, head, and neck have a worse prognosis.

A

True