Cancer Screening Tools Flashcards

1
Q

Nearly all cases of oral squamous cell carcinoma arise from _____________.

A

Precursor epithelial changes (oral epithelial dysplasia)

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2
Q

T/F: Clinical oral exams have good sensitivity and specificity for identifying oral cancer.

A

True

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3
Q

T/F: Trained auxiliaries are nearly as accurate at an oral exam as dentists.

A

True

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4
Q

What is the difference between a screening test and case-finding test?

A

Screening: used on people apparently free of disease

Case-finding: analyze abnormal clinical finding or symptomatic patient for a diagnosis

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5
Q

T/F: The BrushTest is a screening test.

A

False

Case-finding test

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6
Q

T/F: The BrushTest is designed to be used on lesions suspicious for dysplasia or cancer.

A

False

Suspicious lesions get immediate scalpel biopsy

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7
Q

T/F: The BrushTest provides a diagnosis.

A

False

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8
Q

T/F: The BrushTest is the only device we have studied that is not a screening test.

A

True

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9
Q

What is chemiluminescence?

A

Emission of light as the result of chemical reaction

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10
Q

What will normal and abnormal cells look like under the ViziLite?

A
Normal = dark
Abnormal = acetowhite
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11
Q

T/F: There is clear evidence that ViziLite improves detection of oral lesions.

A

False

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12
Q

What is the acronym for VELscope?

A

Visually Enhanced Lesion scope

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13
Q

T/F: VELscope is based on the concept of chemiluminescence.

A

False

ViziLite = chemiluminescence

VELscope = tissue fluorescence

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14
Q

What will normal and abnormal cells look like under the VELscope?

A

Normal = pale green autoflourescence

Abnormal = reduced autofluorescence (dark)

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15
Q

T/F: There is substantial data to support the VELscope as a true screening tool.

A

False

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16
Q

How is the VELscope best used?

A

Evaluate spots under VELscope to take a closer look at via clinical exam

17
Q

T/F: The VELscope can be used in a case-finding role.

A

True

Delineate margin of known lesion

18
Q

Which screening tool incorporates fluorescence and liquid-based cytology?

A

OralID

19
Q

T/F: Most oral cancers are diagnosed in stage III or IV.

A

True

Much lower prognosis

20
Q

What are the high-risk sites for oral cancer?

A

Ventro-lateral tongue, floor of mouth, lateral soft palate/anterior tonsillar pilars

21
Q

What are our current best defenses against oral cancer?

A
  1. Patient education

2. Visual and tactile examination