Meiosis Notes Flashcards
Why Meiosis?
- Reduces chromosome number by ½ (diploid to haploid)
- Formation of sex cells
Major problem arises without meiosis, what is it?
- Each generation would have twice the normal
number of chromosomes after the union of the
sex cells
Homologous Chromosomes
Chromosomes in somatic cells occur in pairs called
Homologous Chromosomes (given from parents -> 1 from mom and one from dad), they look to same and carry
the same type of genetic information
!!!Homologous chromosomes are found only in somatic cells not in gametes!!!!
-Homologous pairs separate in Meiosis I and sister chromatids separate Meiosis II
-The X made of two sister chromatids
-Diploid-> homologus
Haploid vs. Diploid
- Cells with homologous chromosomes have diploid number (2n) of chromosomes
- Gametes have only one member of each pair of homologous chromosomes, therefore gametes have half the normal chromosome number and are called haploid (n)
Number Game
Diploid #:
- Somatic cells
- 2n
- Humans?-> 46
- Homologues -> 23
Haploid #:
- Gametes
- n
- Humans?-> 23
- Homologues?-> 0
Chromosome # = Diploid Number
Ploid= chromosome
Phases of Meiosis
- Meiosis requires two cell divisions of a diploid parent (germ) cell, one right after the other. Each has a specific purpose:
- Meiosis I : homologous chromosomes separate
- Meiosis II: chromatids of each chromosome separate
Synapsis and tetrad
- Synapsis: During Meiosis I, homologous chromosomes come together (they literally sit on top of each other) during prophase I
- Tetrad: Structure formed when chromosomes twist around each other during Prophase I
- Crossing over occurs at what is called the chiasmata- Provides unique combinations of genetic information and contributes to production of unique individuals -> allele swap
- Tetrad: Structure formed when chromosomes twist around each other during Prophase I
Meiosis II: Individual chromatids are separated
- NO INTERPHASE* -> so its not mitosis
- Prophase II:
- Metaphase II:
- Anaphase II:
- Telophase II / Cytokinesis:
Prophase II:
- Chromosomes thicken and darken -> you can see distinct chromosomes
- Spindle fibers appear
- Nuclear membranes disappear
Metaphase II:
-Chromosomes line up down equator of cell and spindle fibers attach at centromeres
Anaphase II:
Chromatids are pulled apart at the centromeres and move to opposite ends of the cell.
Telophase II / Cytokinesis:
- Cell membrane pinches inward splitting cells
- Spindle fibers disappear
- Nuclear membranes form around chromosomes
Interphase I:
-Chromosomes replicate
Prophase I
-Spindle fibers appear
-Nuclear membrane disappears
-Chromosomes coil and become thicker and darker
!!!Homologus pairs join together!! -> tetrad
Metaphase I
- Homologous pairs (TETRADS) line up down equator of cell
- Crossing over can occur here (anytime up until the homologues separate)