Meiosis and Sexual Life Cycles Flashcards

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1
Q

What does heredity mean?

A

Transmission of traits from one generation to the next

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2
Q

What does variation mean?

A

It’s differences between members of a species

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3
Q

What is genetics?

A

Scientific study of heredity and hereditary variation

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4
Q

What is a gene?

A

A stretch of DNA encoding a specific RNA or protein

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5
Q

Locus (loci)

A

The specific location of a gene on a chromosome

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6
Q

What is asexual reproduction?

A
  • Single parents produces offspring with identical genomes
  • Mitosis
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7
Q

What is sexual reproduction?

A
  • Parents produce offspring with unique gene combinations
  • Involves meiosis and fertilization
  • Produces genetic variation
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8
Q

What are gametes?

A

Reproductive cells

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9
Q

What are somatic cells?

A

Any body cell except sperm or egg cells

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10
Q

How many copies of each chromosome do somatic cells have?

A
  • Two copies
  • Diploid
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11
Q

How many copies of each chromosome do gamete cells have?

A
  • One copy each
  • Haploid
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12
Q

What are homologous chromosomes?

A
  • Chromosomes with the same genes at the same loci
  • May carry different alleles
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13
Q

Karyotype

A

A display of the chromosome pairs of a cell arranged by size and shape

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14
Q

How many pairs of chromosomes do humans have?

A
  • 23 pairs
  • 22 pairs of autosomes and 1 pair of sex chromosomes
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15
Q

Sexual life cycle - animals

A
  • Gametes are the only haploid cells
  • A zygote divides through mitosis to grow into a multicellular adult human
  • Adult human germ cells (2n) produce gametes (n) through meiosis
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16
Q

What is fertilization?

A

Gametes (n) join and their nuclei fuse, producing a zygote (2n)

17
Q

Sexual life cycles - plants and some algae

A
  • Meiosis produces haploid spores that undergo mitosis to produce a multi-cellular haploid organism
  • Gametes are produced by mitosis
  • Fertilization produces a diploid zygote that undergoes mitosis to produce a multicellular diploid organism
18
Q

What is the alternation of generations?

A

Includes both diploid and haploid stages that are multicellular

19
Q

Sexual life cycles - most fungi and some protists

A
  • Fertilization produces a unicellular diploid zygotę that undergoes mitosis to produce haploid cells
  • Haploid cells then undergo mitosis to produce unicellular descendants or a multi-cellular haploid organism
  • Gametes are produced from haploid cells via mitosis
20
Q

Meiosis Overview

A
  • Producing haploid cells from diploid cells, involves 2 rounds of cell divisions but one round of DNA replication
  • 4 haploid cells are produced from 1 diploid cell
21
Q

Meiosis I - Prophase I

A
  • Chromosomes condense
  • Spindle forms
  • Nuclear envelope breaks down
  • Crossing over occurs
  • Kinetochore forms
  • Microtubules attach
  • Non-sister chromatid break at points, and homologues held together by the synaptonemal complex in a process called synapsis
22
Q

What is crossing over?

A
  • exchange of DNA between non-sister chromatid during prophase I
  • increases genetic variability
23
Q

What is synapsis?

A

The fusion of chromosomes pairs at the start of meiosis

24
Q

What is chiasma

A
  • point of contact between non sister chromatids
25
Q

Meiosis I - Metaphase I

A

homologous chromosome pairs align at metaphase plate

26
Q

Meiosis I - Anaphase I

A
  • Cohesions breakdown along chromosome arms
  • Homologous chromosomes move to opposite poles
27
Q

Meiosis I - Telophase I and cytokinesis

A
  • Forms two haploid cells
  • Each chromosome still consists of two sister chromatid
28
Q

Meiosis II Overview

A
  • Equivalent to mitosis, ister chromatids split but they are not genetically identical
  • Each haploid cell from meiosis I produces two haploid cells
29
Q

Meiosis II - Prophase II

A
  • mitotic spindle starts to form
  • nuclear envelope fragments
  • kinetochore forms
  • microtubules attach
30
Q

Meiosis II - Metaphase II

A

chromosomes align at metaphase plate

31
Q

Meiosis II - Anaphase II

A
  • cohesion sprung centromere cleaved
  • sister chromatid separate
  • cell elongates
32
Q

Meiosis II - Telophase II and cytokinesis

A
  • nuclei form
  • cells split
  • product is 4 haploid cells
33
Q

What events are unique to meiosis?

A
  • Synapsis and crossing over
  • Alignment and separation of homologous chromosomes
34
Q

What is the main advantage of sexual reproduction?

A

The new combinations of alleles

35
Q

What are the 3 factors that contribute to genetic variability?

A
  1. Independent assortment of chromosomes
  2. Random fertilization
  3. Crossing over
36
Q

What is independent assortment of chromosomes?

A
  • alignment of each pair of homologues is independent of other pairs of homologues 2^n possibilities
  • where n = number of pairs of chromosomes
37
Q

What is random fertilization?

A
  • any sperm and egg can fuse to produce a zygote
  • 2^n * 2^n possibilities
38
Q

What is crossing over?

A
  • produces recombinant chromosomes with unique set of alleles
  • in humans 1-3 crossovers per chromosome