MedSurgs2 Exam1 Flashcards
Anaphylaxis: Type#, Onset time, Caused by
Type 1
Within seconds to minutes
Caused by exposure to specific allergen
Anaphylaxis FX (2)
widespread
↓ blood vessel tone
↓ cardiac output
Anaphylaxis Onset S/S Subj (5)
Uneasiness Apprehension Weakness Anxiety Impending Doom
Anaphylaxis Onset S/S Skin (5)
Generalized itching Urticaria (hives) Erythema Angioedema (swelling of eyes), lips, and tongue Itchy Skin
Anaphylaxis Onset S/S Respiratory (9)
Bronchconstriction Mucosal Edema ↑ Mucous production Respiratory Distress Wheezing, Crackles, Hoarseness, Stridor "Lump in Throat"
Anaphylaxis Onset S/S Cardio (6)
Hypoxemia HypoTN Rapid/Weak Irregular Pulse (also by vasodilation or ↑ capillary leak) Faint Diaphoretic
Anaph. # Criterias
3
Ana. Criteria 1
Onset and Fx (3x3)
Within mins - hrs
Swelling - Swollen lips, uvula, and hives
Respiratory distress - dyspnea, wheezes, low peak expiratory rate
HypoTN r/in ↓ perfusion r/in organ d/fx - r/in LoC, incontinence, hyptonia, absent reflexes
Ana. Criteria 2
Onset and Fx (1 + 1x3)
Within min - hrs of >2 of the following
Any Criteria 1
GI - N/V, cramping, ab. pain
Ana. Criteria 3
Onset and Fx (2)
Within mins - hrs of…
HTN with BPS
Education for Leukemic Pt on Infx Protection (8)
Oral/Hand/Skin Care/Hygiene Ø Crowds Protective Equipment Flu/Pneumonia Vaccines Recgonize S/S of Infx
Leukemia (What is it and the Fx?)
Acute or Chronic?
Cancer r/in uncontrolled production of “Blast” WBC.
r/in production of immature d/fxal cells and ↓ RBC output
Can be both Acute (sudden/short) and Chronic (slow/long).
Leuk. and WBC?
Even though pt might have normal WBC levels, they are immature and Ø fight off infx
Leuk. S/S Cardiovascular (↑ 2, ↓ 1)
↑ HR, RR
↓ BP
Leuk. S/S Respiratory (3)
Murmurs/Bruits
Ab.normal breath sounds
Leuk. S/S Subj. (5)
Fatigue Neurological Changes Headache Fever Bone/Joint pain
Leuk. S/S Skin and GI (4)
Bleeding
Cool/Pallor Skin
Intestinal Changes
Transplants Throughout the Years (10)
Kidney focal point
1912 - transplanting blood vessels
1930 - skin grafting for burns common
end of 1940 - kidney transplant for 6 mo.
1954 - first renal transplants b2n twins
1960 - Imuran (Azathoproine) immunosuppression
↑ Renal transplant survival rates b/c other immunosuppressions.
Liver/Pancreas transplant
↓ Success rate for ♥ transplants 1968 - 1970
Cyclosporine developed
Acute Rejection Onset Graft HLA recognized as...? Type of response Cells do what? R/in?
days - months
HLA antigens are recognized as foreign (non-self)
Type 4 cell-mediated Hypersensitive Response
T Lymphocytes/Macrophages proliferate attach and destroy donor tissue
Cytotoxic antibodies, which further aggravates acute rejection process