Meds Flashcards
Aminoglycosides
“A Mean Old Mysin”
Would be used to treat serious, resistant, life-threatening, Gram negatives infections
• So, treat a mean old infection with a “Mean Old Mycin”
o Examples are: TB, septic peritonitis, fulminating pyelonephritis, septic shock, infection from third degree wound covering >80% of the body
NOT treated by –mycin
Sinusitis, otitis media, bladder infection, viral pharyngitis, and strep throat
All aminoglycosides end in Mycin
• Gentamycin, Vancomycin, and Clindamycin, Streptomycin, Cleomycin, Tobramycin
• Not all drugs ending in mycin are aminoglycosides
o Azithromycin, Clarithromycin, Erythromycin … All have THRO in the middle … So, THRO them off the “Mean Old Mycin” list
- Can cause prolonged QT
What are toxic effects of aminoglycosides
• Mycin—Sounds like Mice (Think ears) … Monitor hearing (#1), balance, tinnitus (ringing of the ear, CN8 toxicity)
• The human ears are shaped like a kidney so another toxic effect of aminoglycosides is nephrotoxicity (Toxic to the kidneys)
o Therefore, monitor Creatinine
The figure 8 drawn inside the ear should remind you of of 2 things
Aminoglycosides
They are toxic to CN8
Administer them q8 hour
There are 2 cases where Mean Old Mycins are given PO
- Hepatic encephalopathy (or hepatic coma) where ammonia level gets too high
- Pre-op bowel surgery: to sterilize the bowel before surgery
The #1 action of an “oral mycin”
Sterilize the bowel
Who can sterilize my bowel?
Neo Kan
o Neomycin and Kanamycin
When is the trough drawn
it is always drawn 30 minutes before next dose
When is a peak drawn for SubL
5-10 mins after drug is dissolved
When is a peak drawn for IV
15-30 min after bag is empty (drug is finished)
When is a peak drawn for IM
30-60 min
CCBs (Calcium channel blockers)
are like Valium for the heart
• They relax and slows down the heart
• In other words, CCBs have negative inotropic, chronotropic, dromotropic effects on the heart
When do you want to relax and slows down the heart?
To treat “A, AA, AAA”
• Antihypertensive
• AntiAnginal drugs (decreasing oxygen demand)
• AntiAtrialArrhythmia
