Medications for HF Flashcards
Digoxin MOA
WEAK positive inotrope
Inhibits Na/K ATPase pump
Digoxin Therapeutic Use
Used for HFrEF + Atrial dysrythmias
decrease conduction through AV node, decreases automaticity in SA node.
Digoxin Side Effects
MAJOR ADVERSE EFFECT - CARDIOTOXICITY (dysrhythmias) with increased risk w/ hypokalemia (concurrent use of loop or HCTZ diuretics)
VERY narrow window for therapy
GI AND CNS effects too
HALO EFFECT
Digoxin Interactions
NUMEROUS
Digoxin Considerations
Monitor therapeutic windows
Used for atrial dysrhythmias only, not ventricular
Hydralazine/Isosorbide
Used for HF and persistent HTN patients
Inotropic agents
Dobutamine, milrinone, dopamine
IV ONLY short term use