1
Q

Digoxin MOA

A

WEAK positive inotrope
Inhibits Na/K ATPase pump

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Digoxin Therapeutic Use

A

Used for HFrEF + Atrial dysrythmias

decrease conduction through AV node, decreases automaticity in SA node.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Digoxin Side Effects

A

MAJOR ADVERSE EFFECT - CARDIOTOXICITY (dysrhythmias) with increased risk w/ hypokalemia (concurrent use of loop or HCTZ diuretics)
VERY narrow window for therapy

GI AND CNS effects too
HALO EFFECT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Digoxin Interactions

A

NUMEROUS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Digoxin Considerations

A

Monitor therapeutic windows
Used for atrial dysrhythmias only, not ventricular

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Hydralazine/Isosorbide

A

Used for HF and persistent HTN patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Inotropic agents

A

Dobutamine, milrinone, dopamine

IV ONLY short term use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly