Medications/DMARDs Flashcards
name the 6 drug families that are given for ischaemic heart disease
- ACE inhibitors
- Statins
- B-blockers
- Calcium channel blockers
- nitrates
- others ie nicorandil
5 drug families given for hypertension
- ACE inhibitors
- angiotensin 2 receptor antagonists
- B-blockers
- Calcium channel blockers
- Diuretics
what are the 4 drugs given for heart failure?
- ACE inhibitors/angiotensin 2 receptor antagonists
- B-blockers
- diuretics
- digoxin
what medication id given in valvular disease?
anticoagulants
what medications are given for arrythmias?
- Anti-coagulants
- B-blockers
- Calcium agonists
- Digoxin
- Amiodarone
what 3 types of drugs can give MRONJ?
- bisphosphonates
- denosumab
- anti-angiogenics
name 2 anti-angiogenics
- sunitinib
2. bevacizumab
what are anti-angiogenics given for?
as cancer tx (esp if bone metastases)
what are some of the oral effects of anti-angiogenics (3)
- taste d
- oral mucositis
- vomitting
what is denosumab given for?
- postmenopasal women with osteoporosis
- men with prostate cancer at risk of fractures
- bone metastases
what are the 5 medication groups that are given to patients with asthma?
- short acting B-2 agonist
- long acting B-2 agonist
- steroid
- anti-leukotrienes
- systemic steroids
name a systemic steroid?
- prednisolone
what are all the main uses for prednisolone?
- asthma
- COPD
- rheumatoid arthritis
- SLE
- giant cell (temporal) arteritis
- prophylaxis of episodic cluster headaches
- ulcerative colitis
- chrons disease
what (in addition to all the asthma drugs) are taken for COPD?
- short acting muscarinic antagonists (ipatropium)
- long acting muscatinic antagonists (tiotropium)
- mucolytic (carbonaisteine)
- antibiotics (azithromycin)
name 2 corticosteroid drugs
- hydrocortisone
2. triamcinolone
what are the 2 possible side effects of corticosteroids that require monitoring>
- BP changes
- hyperglycaemia
what are some oral effects of corticosteriods?
- candidosis
- MRONJ
what are 2 diseases that can occur due to taking corticosteroids?
- cushing syndrome
- osteoperosis
name some DMARDs
- methotrexate
- ciclosporin
- hydrochloroquine
- azathiopine
- sulfasalazine
- gold
- lefunomide
- myocophenolate mofietil
2 ways methotrexate can be delivered are?
orally
subcutaneous injection
2 ways that azathiopine can be administered are?
orally
intravenously
what is the dose of methtrexate given?
7.5 - 15mg (max is 25mg)
taken 1x a week
what is the dose of azathipine given?
1-3mg/kg
what are the dental aspects of DMARDs?
- oral ulceration
- neutropenia ( increased susceptibility to infection)
what patients will receive biologics - monoclonal antibody therapy?
those who have failed to respond to at lease 2 DMARDs
