Medications Affecting the Cardiovascular System Flashcards
Indications of Angiotensin-Converting Enzyme (ACE) Inhibitors
- hypertension
- HF
- help diabetics prevent kidney problems
What does ACE inhibitors act as
vasodilator
ACE inhibitors examples
-enalapril
-lisinopril
-captopril
(ends in -pril)
What medication ends in (-pril)
ACE inhibitors
What should ACE inhibitors be monitored for
- hypotension
- cough
- edema
- increased BUN
What are antithrombotic agents for
- decreases coagulability (capable of forming clots)
- prevents formation of new clots
What will antithrombotic agents do to existing clots
keep existing clots from growing larger
What does antithrombotic agents not do
dissolve existing clots
What is a contraindication of antithrombotic agents
active bleeding
What does Heparin do
-prevents blood clots
-stops the growth of clots that have already formed
(does not decrease clot that has already formed
What is the antidote of Heparin
Protamine Sulfate
How is Heparin administered
- subQ or IV
- used in small amounts to prevent blood clots from forming in catheters
How often to give Heparin
subQ every 12 hr
-continuous or intermittent IV infusion
What should be monitored when giving Heparin
APTT every 4-6 hour until appropriate dose is determined, then monitor daily
What does PT (prothrombin time) test measure
how much warfarin (coumadin) a person has in there system
What does Warfarin interfere with
vitamin K dependent coagulation factors
Difference from Warfarin and Heparin
Warfarin action is more prolonged then heparin
Administration teaching for Warfarin
Take this medication the same time each day
What lab test does Warfarin affect
PT/INR values
What are antiplatelet agents for
stops platelets from sticking together and forming a clot
What are antiplatelet agents contraindications for
person who has an active bleeding
What should be monitored when taking antiplatelet agents
bleeding
Types of antiplatelet agents medications
- Aspirin.
- Clopidogrel
- Ticlopidine
- Abciximab
- Tirofiban
What are Thrombolytics
dissolves thrombi (blood clot) in the coronary arteries and restores myocardial blood flow during first 6 hours of a MI
Thrombolytics contraindications
- active bleeding
- hypertension
- pregnancy
- recent stroke, surgery, trauma