Medications Flashcards
What is the dose of Benadryl that you would give to a patient having a mild allergic reaction (diphenhydramine)?
25-50 mg IV/IO/IM/PO
What is the indication for Benadryl (diphenhydramine)?
Allergic reaction
Pediatric allergic Rxn
What is a contraindication for Benadryl (diphenhydramine)?
Asthma
Infants less than 3 months
Narrow angle glaucoma
Prostatic Hypertrophy
What dose of diphenhydramine (Benadryl) would you give to a pediatric patient experiencing a mild allergic rxn?
1mg/kg IV/IO/IM
What is the generic name for Zofran?
Ondansetron
What is the trade name for ondansatron?
Zofran
What is the action of Zofran (ondansetron)?
Zofran (ondansetron) antagonizes serotonin receptors.
What are the indications for the use of Zofran (ondansetron)?
Abdominal pain
Vomiting & diarrhea
Pediatric vomiting & diarrhea
What are the contraindications for the use of Zofran (ondansetron)?
Hypersensitivity
Concomitant use of apomorphine
What are the side effects of Zofran (ondansetron)?
Headache
Drowsiness
What is the adult dose/route of Zofran (ondansetron)?
ABDOMINAL PAIN — 4mg IV/IM/IO/ODT may repeat in 15 minutes
VOMITING/DIARRHEA — 4mg IV/IO/ODT may repeat in 15
What is the pediatric dose/route of Zofran (ondansetron)?
Serious S/S — no: 0.2mg/kg PO/ODT (max. 4mg)
Yes: 0.2mg/kg ODT -or-
0.15mg/kg IV/IO
What are any special considerations for the use of Zofran (ondansetron)?z
It prolongs the QT interval
What pregnancy category is Zofran (ondansetron)?
Pregnancy category B
What is the trade name for promethazine?
Phenergan
What is the generic name for Phenergan?
promethazine
What class of medication is Zofran (ondansetron)?
Antiemetic
What is an antiemetic?
a drug that prevents vomiting
What is the class of Phenergan (promethazine)?
It is an antihistamine and a antiemetic drug
What is the action of Phenergan (promethazine)?
It blocks H1 receptors
Possesses anticholinergic properties
What are the indications for Phenergan (promethazine)?
Abdominal pain
Vomiting & diarrhea
What are the contraindications of Phenergan (promethazine)?
Children < 2
Lactating women
What are the side effects of Phenergan (promethazine)?
Sedation
Respiratory depression
Induced asthma
What is the adult dose/route for Phenergan (promethazine)?
12.5mg IV/IO/IM repeat x 1 (as needed)
What is the pediatric dose/route for Phenergan (promethazine)?
None
What are any special considerations for the use of Phenergan (promethazine)?
Choose lower dose if reaction is suspected (ie. Age > 60)
When giving IV dilute with 10mL of NaCl & PUSH SLOWLY
What pregnancy category is Phenergan (promethazine)?
Pregnancy category C
What is the trade name for albuterol?
Proventil
Ventolin
What is the generic name for Ventolin and Proventil?
albuterol
What class of medication is albuterol?
Sympathomimetic
What is the action of albuterol (ALS)?
Bronchodilation
What are the indications for albuterol?
Allergic Rxn/anaphylaxis
Adult COPD/Asthma
Ped. Allergic Reaction
Ped. Respiratory Distress
What is the contraindication for albuterol?
Hypersensitivity
What are the side effects of albuterol?
Tremors Paradoxical bronchospasm Dizziness Nausea Angioedema
What is the adult dose of abuterol?
2.5-5.0mg NEB +/- 0.5mg ipratropium repeat x 3 as needed
What’s is the pediatric dose of albuterol?
Allergic Rxn (mod/severe) 2.5-5.0mg NEB +/- 0.5mg ipratropium repeat x 3 as needed
Stridor 1.25-5.0mg NEB
Wheezing
(greater than or equal to 12 mo.) 1.25-5.0mg NEB repeat x 3 as needed
(less than 12 mo.) 1.25-2.5mg NEB repeat x 3 as needed
MAY BE USED IN CONJUNCTION WITH ATROVENT
What are the special considerations for albuterol?
Use with caution in patients with cardiovascular disease
What pregnancy category is albuterol?
C
What is the generic name of Xopenex?
Levalbuterol HCL
What is the trade name of levalbuterol HCL?
Xopenex
What class of medication is Xopenex?
Beta 2 agonist
What is the action of levalbuterol (Xopenex)?
Activates beta 2 adrenergic receptors on bronchial smooth muscles (bronchodilator)
What are the indications for levalbuterol (Xopenex)?
Allergic Rxn/Anaphylaxis
Adult COPD/Asthma
Ped. Allergic Rxn
Ped Respiratory distress
What are the contraindications of levalbuterol (Xopenex)?
Hypersensitivity
What are the side effects of levalbuterol (Xopenex)?
Nervousness
Tremors
Tachycardia
What is the adult dosage of levalbuterol (Xopenex)?
Adults & adolescents 12 years or > 0.63mg/3mL NEB
What is the Ped dosage of levalbuterol (Xopenex)?
(6-11 years) 0.31mg/3mL
What is the pregnancy category for levalbuterol (Xopenex)?
C
How long does levalbuterol (Xopenex) last in the system?
8 hrs
What is the generic name for Atrovent?
Ipratropium
What is the trade name for ipratropium?
Atrovent
What class of medication is Atrovent (ipratropium)?
Anticholinergic (parasympathetic)
What is the action of Atrovent (ipratropium)?
Bronchodilation (antagonizes action of acetylcholine)
What are the indications for Atrovent (ipratropium)?
Adult COPD/Asthma
Allergic Reaction/Anaphylaxis
Pediatric Allergic Reaction
Pediatric Respiratory Distress
What are the contraindications of Atrovent (ipratropium)?
Hypersensitivity to: Atrovent, atropine, soy, peanuts
What are the side effects of Atrovent (ipratropium)?
Dizziness/palpitation
Bronchitis
Angioedema
Paradoxical bronchospasms
What are the adult dosages of Atrovent (ipratropium)?
Allergic Reaction/Anaphylaxis – 0.5mg (500mcg) repeat x 3 as needed
Adult COPD/Asthma - 0.5mg repeat x 3 as needed (may be used in conjunction with Albuterol)
What is the pediatric dosage of Arrovent (ipratropium)?
Allergic Rxn — 0.5mg repeat x 3 as needed
Respiratory Distress — 0.5mg repeat x 3 as needed
What pregnancy category is Atrovent (ipratropium)?
B
What is the generic name for Solu-Medrol?
Methylprednisolone
What is the trade name for methylprednisolone?
Soul-Medrol
What class of medication is Solu-Medrol (methylprednisolone)?
Corticosteroid
What is the action of Solu-Medrol (methylprednisolone)?
Reduces pulmonary inflammation & mucous production
Reverses capillary permeability
What are the indications for Solu-Medrol (methylprednisolone)?
Adult COPD/Asthma
Allergic Rxn/Anaphylaxis
Ped Allergic Rxn
Ped respiratory distress
What are the contraindications for Solu-Medrol (methylprednisolone)?
Hypersensitivity
What are the side effects for Solu-Medrol (methylprednisolone)?
Rare prehospital
What is the adult dose of Solu-Medrol?
Mod/severe allergic Rxn - 125mg IV/IO
COPD/Asthma - 125mg IV/IO
What is the ped dosage of Solu-Medrol (methylprednisolone)?
Allergic Rxn (mod/severe) - 2mg/kg IV/IO max. 125mg
Respiratory Distress - stridor - 2mg/kg IV/IO max. 125mg
Wheezing - 12 mo. or greater? Yes - 2mg/kg IV/IO (max 125mg)
No - 1st episode? None
2nd or more? 2mg/kg IV/IO max. 125mg
What are the special considerations for Solu-Medrol (methylprednisolone)?
IM dosing only if indicated by local protocol
What pregnancy category is Solu-Medrol (methylprednisolone)?
C
What is the pregnancy category for nalaxone?
C
What are any special consideration for nalaxone?
May induce withdrawals
Use cautiously in drug-dependent adults/newborns
What is the pediatric dose of nalaxone?
0.1mg/kg IV/IO/IM/IN/ETT max. 2mg
Titrated to effect
Adequate oxygenation/ventilation
Not to be given to restore consciousness
What is the adult dose of nalaxone?
0.4-2mg IV/IO/IM/IN/ETT
Titrated to effect
Adequate ventilation/oxygenation
Not to be given to restore consciousness
What are the side effects for nalaxone?
Nausea/vomiting
Drowsiness
What are the contraindications of nalaxone?
Hypersensitivity
What is the indications for nalaxone?
Overdose/toxic ingestion
Pediatric overdose/toxic ingestion
Naloxone is generic for ?
Narcan
What is the class for Narcan ( Naloxone)?
Narcotic antagonist
What action does Narcan provide (Naloxone)?
Binds opioid receptors and blocks the effects of narcotics
What are the indications for Narcan( Naloxone)?
#31 overdose/toxic ingestion #60 ped overdose/toxic ingestion
What are the contraindications for Narcan (Naloxone)?
hypersensitivity
What are the side effects for Narcan ? (Naloxone)
Nausea
Drowsiness
What is the adult Dosage for Narcan ( Naloxone)?
0.4 -2mg IV/ IO/ IM/ IN/ ETT
What is the dosage for Peds for Narcan( Naloxone)?
0.1 mg/kg IV/ IO/ IM/ IN/ ETT
Max 2mg
What pregnancy category is Narcan (Naloxone)?
C
What is the trade name for glucagon?
Glucogen
What is the generic name for Glucogen?
glucagon
What is the class for Glucogen (glucagon)?
Antihypoglycemic agent
Hormone
What is the action of Glucogen (glucagon)?
Causes the breakdown of glycogen to glucose
Increases chronotropy
Increases inotropy
What are the indications for Glucogen (glucagon)?
Diabetic adult
Overdose/toxic ingestion
Ped. Diabetic
Ped. Overdose/toxic ingestion
What are the contraindications of Glucogen (glucagon)?
Patients with inadequate glucogen stores
Malnutrition
Alcoholic
Diabetic
What are the side effects of Glucogen (glucagon)?
Rare in emergency setting
What is the dosage for Glucogen (glucagon)?
Diabetic — Blood sugar less than or equal to 69mg/dl and symptomatic:
1-2mg IM repeat in 15 minutes if needed
OD/TI — 2mg IV/IO may repeat in 15 minutes
What is the pediatric dose of Glucogen (glucagon)?
Diabetic — blood sugar less than or equal to 69mg/dl & symptomatic
0.1mg/kg IM may repeat every 15 minutes as needed MAX 1mg
OD/TI — beta blocker OD
0.1mg/kg IV/IO/IM max. 2mg
What are the special considerations for the use of Glucogen (glucagon)?
Use with caution in patients with heart/renal diseases.
What pregnancy category is Glucagen (glucagon)?
B
What is the trade name for dextrose 50%?
D50
What is the trade name for d50?
Dextrose 50%
What class is dextrose 50% (d50)?
Carbohydrate
What is the action of dextrose 50% (d50)?
Increases circulating glucose
Transient osmotic diuretic
What are the indications for the use of dextrose 50 (d50)?
Adult diabetic
Pediatric diabetic
What are the contraindications for dextrose (d50)?
None in the emergency setting
What is the dose of dextrose (d50)?3
Awake/Alert/symptomatic BS 69mg/dl or less
12.5g IV/IO (after considering oral glucose)
ALOC BS 69mg/dl or less
12.5-25g IV/IO
Repeat every 5 minutes until BS is greater than or equal to 70mg/dl
What are the side effects of dextrose 50% (d50)?
Extravasation
Phlebitis
Hyperglycemia
What is the pediatric dose of dextrose (d50)?
Awake/alert/symptomatic
BS 69mg/dl or less
Consider oral glucose
ALOC BS 69mg/dl or less
Less than 1month —D10 6ml/kg IV/IO repeat as needed
1month— 2 years D25 4ml/kg IV/IO Repeat as needed
Older than 2 years D50 2ml/kg IV/IO max 25g per dose repeat as needed
Repeat every 5 mins until BS is higher than 70mg/dl
What are special considerations for the use of dextrose 50% (d50)?
Consider d50 for any pt with ALOC/AMS
what pregnancy category is dextrose (d50)?
C
What is the trade name for thiamine?
Betaxin
What is the generic name for Betaxin?
thiamine
What class of medication is thiamine?
vitamin (B1)
What action is thiamine (Betaxin)?
assists in carbohydrate metabolism
What are the indications of thiamine (Betaxin)?
DTs
Malnutrition
Coma of unknown origin
What are contraindications for thiamine (Betaxin)?
Hypersensitivity
What are the side effects of thiamine (Betaxin)?
Hypotensive (from rapid push)
N/V
What is the dose of thiamine (Betaxin)?
100mg slow IVP
What is the pregnancy category for thiamine (Betaxin)?
A
What is the action of nalaxone?
It binds to opioid receptors and blocks the effects of narcotics
What class of medication is nalaxone?
Narcotic antagonist
What is the trade name for nalaxone?
Narcan
What is the generic name for Narcan?
Nalaxone
What is the dose of diphenhydramine (Benadryl) that you would give to an adult have a Moderate/severe allergic Rxn?
25-50mg IV/IO/IM (if not already given PO)
What are the side effects for the administration of diphenhydramine?
Drowsiness/sedation
Anxiety/tremors
Thickens bronchial secretions
What dose of Benadryl would you give to a pediatric patient experiencing a moderate/severe allergic rxn?
1mg/kg IV/IO/IM (if not given PO)
What are the special considerations for the administration of Benadryl?
Peds OD: hallucinations, convulsions, death
What class of medication is Benadryl?
Antihistamine
What is the action of diphenhydramine?
Blocks H1 receptors
Possesses anticholinergic and antiemetic properties
What pregnancy category is Benadryl?
B
What class of medication is epi?
Sympathomimetic
What is the action of epi?
Vasoconstriction/relaxes bronchiole smooth muscles
What are the side effects for epi?
Anxiety/palpitations
Headaches
What are the contraindications for the use of epinephrine?
None
You responded to a call for a 25y/o patient experiencing wheezing. Your protocol calls for the administration of epinephrine. What dose/route could you administer?
0.3-0.5mg IM
You have been dispatched to a 6 y/o allergic reaction. Your protocol suggests the administration of epinephrine. How much and by what route could you administer this medication?
0.01mg/kg IM
MAX 0.3mg
Repeat in 5 min if no improvement
You are responding to a 19 y/o patient with stridor. Your protocols suggests the administration of epi. What dose/route could you administer?
1mg in 2mL of NS NEB
What is the dosage of epi for a pediatric patient experiencing wheezing?
If they are less than 12 months and it is their first time, 1mg in 2mL of NS NEB
Your 45 y/o patient is experiencing wheezing as a result of his COPD. Your protocol calls for the administration of epi. What dose/route could you administer this epinephrine?
0.3-0.5mg IM
You respond to a 5 y/o patient experiencing stridor. Your local protocol suggests the administration of epinephrine. What dose/route could you administer?
1mg in 2mL of NS NEB
may repeat once
-or-
0.01mg/kg IM
Max 0.3mg
What is the action of fentanyl?
It binds to opioid receptors and produces an analgesic effect
Your patient is having an moderate/severe allergic reaction. What dose range of epinephrine would you consider?
0.3-0.5mg IM
Repeat in 5 minutes if no improvement
What pregnancy category is epinephrine?
C
What are special considerations for the use of epinephrine?
Any patient 50 years or older
Any patient with cardiac disease
Any patient on: digitoxin or beta blockers
If the patient has a HR of 150 or greater, administer half the dose (0.15-0.25mg)
Epi 1:1000 May be administered IV (consult med control)
What are contraindications for the use of fentanyl (sublimaze)?
Hypersensitivity
Known intolerance to opioids
What are the side effects for the use of fentanyl?
Respiratory depression/apnea
Muscle rigidity
Bradycardia
What is the generic name of fentanyl?
Sublimaze
Fentanyl (sublimaze) is in what class of medication?
opioid analgesic
What are special considerations for the use of fentanyl (sublimaze)?
Avoid use if SBP
You are about to perform RSI on your patient. How much fentanyl will you administer?
50-75mcg IV/IO
repeat 25mcg every 20 minutes as needed
Max 200mcg
What are the indications for the use of fentanyl (sublimaze)?
Airway RSI
Adult Pain Control
Pediatric Pain Control
What pregnancy category is fentanyl?
C
How much fentanyl will you administer to a pediatric patient experiencing pain?
1mcg/kg IV/IM/IN
may repeat 0.5mcg every 5 minutes as needed
Max 2mcg/kg
What is the generic name for atropine?
Atropen
What class of medication is atropine?
Anticholinergic (parasympatholytic)
What is the action of atropine?
Blocks acetylcholine
Increases heart rate
What are the indications for the use of atropine?
Bradycardia, Pulse Present
Pediatric bradycardia
WMP nerve agent
What are the contraindications for the use of atropine?
High degree heart block
Pts predisposed to narrow angle glaucoma
What are the side effects of atropine?
V-fib
SVT
Dizziness
N/V
Your patient is bradycardic, how much atropine will administer?
0.5-1mg IV every 3-5 minutes (max. 3mg)
ET max. 6mg
What is the organophosphate dose of atropine?
1-2mg IV/IO
Your pediatric patient you just intubated has become bradycardic. How much atropine will you administer?
0.02mg/kg IV/IO (max. 1mg) may repeat in 3-5 minutes
What is the pediatric organophosphate dose?
0.05mg/kg IV/IO
What are special considerations for the use of atropine?
May be given other route per med control
For ET dose, double the dose
What is the pregnancy category of atropine?
C
What is the trade name for lidocaine?
Xylocaine
What class of medication is lidocaine (xylocaine)?
Anesthetic
Antiarrythmic med
What is the action of lidocaine (xylocaine)?
Stabilizes neuronal membrane by inhibiting ionic fluxes
What are the indications for the use of lidocaine (xylocaine)?
Airway, RSI
VF, pulseless VT
Ped VF pulseless VT
What are contraindications for the use of lidocaine?
WPW syndrome
2nd or 3rd degree heart block
Hypersensitivity to corn products
What are the side effects of lidocaine?
Dizziness
N/V
You are preparing to intubate your 25 y/o trauma patient. What is the dose/route of lidocaine you could give him to prevent his ICP?
1.5mg IV/IO bolus; 3mg ETT (max. 3mg/kg)
You have a pulseless VT pediatric patient. What dose/route could you administer your lidocaine?
1mg/kg IV/IO (max. 100mg) may repeat 0.5mg/kg
Max 3mg/kg
What are special considerations for the use of lidocaine?
Use with caution in hypotensive pts
What pregnancy category is lidocaine?
B
What is the trade name for midazolam?
Versed
What class is Versed (midazolam)?
Benzodiazepine
What is the action of midazolam (versed)?
Sedative
Hypnotic
What are the indications for the use of midazolam (versed)?
Seizures
Pediatric seizures
Behavior emergencies
What are the contraindications for the use of versed?
Hypersensitivity
Shock
Narrow angle glaucoma
Acute alcohol intoxication
What are the side effects for the use of versed?
Respiratory depression
Apnea
What are the special considerations for the use of versed?
Do not delay IM administration for IV/IO Access
Titrate slowly
May dilute to facilitate slower administration
Schedule IV control
What pregnancy category is versed?
D
What is the adult dose of versed?
0.5-2.5mg IV/IO
5mg IM
2mg IN
May repeat every 3-5 minutes (max 5mg)
What is the pediatric dose of versed?
- 1-0.2mg/kg IV/IO (max 2mg)
- 2mg/kg IN (max 2mg)
- 2mg/kg IM (max 10mg)
What is the trade name for recuronium?
Zemuron
What class of medication is recuronium?
Nondepolarizing neuromuscular blocking agent
What is the action of recuronium?
Paralytic
What are the indications for the use of recuronium?
Airway RSI
What are the contraindications for the use of recuronium?
Hypersensitivity
What are the side effects for the use of recuronium?
N/V
Prolonged skeletal muscle weakness/atropy
What is the adult dose of recuronium?
1mg/kg IV/IO may repeat x 1
What is the pediatric dose of recuronium?
None
What pregnancy category is recuronium?
C
What are the special considerations for the use of recuronium?
Onset is longer than succinylcholine. May take up to 3-5 minutes
Only use is succinylcholine is contraindicated
What is the trade name for etomidate?
Amidate
What class is etomidate (amidate)?
Anesthetic agent
What is the action for etomidate (amidate)?
Sedative :
Hypnotic
What are the indications for etomidate (amidate)?
Airway RSI
Induced hypothermia
What are the contraindications for etomidate (amidate)?
Hypersensitivity
Patients less than 10 years
What are the side effects for etomidate (amidate)?
Adrenal suppression
Injection site pain
Tonic skeletal muscle movements
What is the adult dose for etomidate (amidate)?
0.3mg/kg IV/IO
Usual does 20mg
What is the pediatric dose for etomidate (amidate)?
None
What are the special considerations for etomidate (amidate)?
Use with caution in hypotensive patients and patients where respirations are suppressed
What is the pregnancy category etomidate (amidate)?
C
What is the trade name for Succinylcholine?
Quelcin
What class is succinylcholine (quelicin)?
Paralytic
What is the action for succinylcholine (quelicin)?
Airway RSI
What are the contraindications for succinylcholine (quelicin)?
Burns less than 24 hours
Chronic neuromuscular disease
ESRD
What are the side effects for succinylcholine (quelicin)?
Apnea
Hyperkalemia
Anaphylaxis
Malignant Hypothermia
What is the adult dose/route of succinylcholine (quelicin)?
1.5mg/kg IV/IO may repeat x1
What is the pediatric dose for succinylcholine (quelicin)?
None
What are the special considerations for succinylcholine (quelicin)?
Consider premeditating with atropine
Premeditating with lidocaine may blunt any increase in ICP
What is the pregnancy category succinylcholine (quelicin)?
C
What is the tear name for Vecuronium bromide?
Norcuiron
What class is vercuronium bromide ( norcuiron)?
Paralytic
What is the action for vercuronium bromide ( norcuiron)?
Neuromuscular blocking agent
What is the indications for vercuronium bromide ( norcuiron)?
Airway RSI
Post Resuscitation
Induced hypothermia
What are the contraindications vercuronium bromide ( norcuiron)?
Patients with chronic neuromuscular disease
What are the side effects vercuronium bromide ( norcuiron)?
Apnea
Muscular skeletal weakness/prolonged atrophy
Hypotension/tachycardia
Bronchospasm
What is the adult dose for vercuronium bromide ( norcuiron)?
10mg (0.1mg/kg) IV/IO (If needed for patients movement)
10mg IV/IO (If needed)
10mg IV/IO (If needed x 1 dose)
What is the pediatric dose for vercuronium bromide ( norcuiron)?
None
What are the special considerations for vercuronium bromide ( norcuiron)?
Paralytic therapy should be started after sedation
Use with caution in patients with poor renal function
Ongoing sedation should be maintained and monitored periodically
What is the pregnancy category for vercuronium bromide ( norcuiron)?
C
What is the trade name for Oxymetazoline HCL?
Afrin
What class is Oxymetazoline ( Afrin)?
Sympathamimetic
What is the action for Oxymetazoline (Afrin)?
Antagonizes a1 and a2 adrenergic receptors
Vaso Constriction
What are the indications for Oxymetazoline (Afrin)?
Epistaxis
Nasotracheal intubation
What are the contraindications for Oxymetazoline (Afrin)?
Hypersensitivity
Significant hypertension
What are the side effects for Oxymetazoline (Afrin)?
Trembling
Nervousness
Headache,dizziness,drowsiness
Blurred vision
What is the adult dose for Oxymetazoline (Afrin)?
2 sprays in affected nostrils
What is the pediatric dose for Oxymetazoline (Afrin)?
1 - 2 sprays in affected nostrils
What are the special considerations for Oxymetazoline (Afrin)?
Use with caution in patients with narrow angle glaucoma
Use with caution in lactating women
What is the pregnancy category for Oxymetazoline (Afrin)?
C
What is the trade name for Vasopressin?
Pitressin
What are the protocols that warrant the use of vasopressin?
Asystole, PEA, and V-Fib
What class of medication is vasopressin?
Nonadrenergic vasoconstrictor
Posterior pituitary hormone (ADH)
What is the mechanism of action of vasopressin?
Vasoconstrictor.
Targets the V1 receptors in the smooth muscle of vessels
Targets the V2 receptors in the kidney promoting fluid absorption
What are the indications for the use of vasopressin?
V Fib
Pulseless V Tach
Asystole
PEA
What are the contraindications of the use of vasopressin?
None in cardiac arrest
Responsive patients with cardiac disease
What are the side effects of vasopressin?
Cardiac ischemia Angina Headache Vertigo Diaphoresis
What is the adult dose of vasopressin?
40 units IV/IO (may be used to replace 1st or 2nd dose of epinephrine)
What is the pediatric dose of vasopressin?
None
What pregnancy category of vasopressin?
C
What are any special considerations for the use of vasopressin?
EMS will only use for patients without a pulse
What is the trade name for dopamine?
Intropin
What are the protocols associated with the use of dopamine?
Bradycardia Hypotension Post Resuscitation PEA Pediatric Hypotension
What class of medication is dopamine?
Adrenergic agonist
Inotropic
Vasopressin
Natural catecholamine
At what dose does dopamine stimulate dopaminergic receptors dilating renal, mesenteric, and cerebral arteries?
1-2mcg/kg/min
At what dose does dopamine act on beta receptors increasing Inotropy and chronotropy?
2-10mcg/kg/min
At what dose does dopamine act on alpha and beta receptors beginning vasoconstriction of peripheral arteries and veins?
10-20mcg/kg/min
On what dose does dopamine act on alpha receptors only and mimic the effects of norepinephrine?
> 20mg/kg/min
What receptors does dopamine act on?
Alpha, beta1, and dopaminergic receptors.
What are the mechanisms of action of dopamine?
Stimulates alpha, beta1, and dopaminergic receptors.
Does not increase oxygen demand as much as epinephrine.
Has greater effect on systolic pressure than diastolic pressure (widening the pulse pressure)
What are the indications for the use of dopamine?
Hypotension and/or bradycardia associated with:
•cardiogenic shock
•septic shock
•neurogenic shock
•anaphylaxis shock after epi 1:1000 had been given
Hypotension after return of spontaneous circulation following cardiac arrest
Symptomatic bradycardia unresponsive to atropine
For the correction of hemodynamic imbalances present during shock due to: •MI •Trauma •Endotoxic septicemia •Open Heart Surgery •Renal failure •Chronic cardiac decomp. (CHF)
What are the contraindications for the use of dopamine?
- Hypovolemia (without fluid replacement)
- Patients with known pheochromocytoma (adrenal tumor)
- V-Tach, V-Fib, or other ventricular arrhythmias
- Known hypersensitivity (including sulfites)
What are the side effects of dopamine?
Nervousness Headache Dysrrhythmias Palpitations Chest pain Dyspnea N/V Tachycardia Skin & soft tissue necrosis Severe hypertension (excessive vasoconstriction) Cardiac conduction abnormalities Anxiety
What is the dose for the use of dopamine? (Adult& Ped)
2-20mcg/kg/min tot rate to systolic BP of 90mmHg
Titrate to systolic BP appropriate for age
What are any special considerations for the use of dopamine?
Dopamine is deactivated by alkaline solutions (do not administer in same line)
Can worsen SVT and ventricle arrhythmias
Dosage of >20mcg/kg/min cause necrosis (by squeezing down on vessles)
Onset
What pregnancy class is dopamine?
C