Medicatie 4: hematologie Flashcards

1
Q

Fenprocoumon

A

vitK antagonist, coumarinederivaat
Onderhoud AF en hoge CHADS2V, trombosebeen, longembolie, kunstklep
Bloedingen, veel geneesmiddelinteracties

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2
Q

Nadroparine

A

Heparine (IIa en Xa remmer)
Initiële behandeling arteriële en veneuze trombose
Bloedingsneigingen

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3
Q

Bijwerkingen trombocytenaggregatie remmers

A

Occult bloedverlies, hematomen

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4
Q

Trombocytenaggregatie remmers

A

Acetylsalicylzuur/carbasalaatcalcium, clopidogrel, dipyridamol
Occult bloedverlies, hematomen

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5
Q

Acetylsalicylzuur, carbasalaatcalcium

A

Trombocytenaggregatieremmers
Na hartinfarct, TIA/CVA icm dipyridamol
Dyspepsie, overgevoeligheid, occult bloedverlies, hematomen

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6
Q

Clopidogrel

A

Trombocytenaggregatieremmer
1e keuze na TIA/CV obv athrosclerose
Dyspepsie, bloedbeeldafwijkingen, occult bloedverlies, hematomen

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7
Q

Dipyridamol

A

Trombocytenaggregatieremmer
Bij CVA naast acetylsalicylzuur
Hoofdpijn, duizeligheid, occult bloedverlies, hematomen

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8
Q

Pravastine

A

cholesterolsynthese remmer
Na hartinfarct of TIA/CVA
Minste interacties met CYP450 > langere T1/2
Maagdarmklachten, spierpijnen

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9
Q

Simvastatine

A

cholesterolsyntheseremmer
Na hartinfarct of TIA/CVA, DM
Meest potent
Maagdarmklachten, spierpijnen

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10
Q

Cholesterolsynthese remmers

A

Pravastine, simvastatine
Na hartinfarct of TIA/CVA
Maagdarmklachten, spierpijnen

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11
Q

Apixaban

A

NOAC (Xa-remmer)
Alternatief voor fenprocouron, niet bij kunstklep
Bloedingen, geen antidotum

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