Med neuro exam 2 lect Flashcards
pontine reticulospinal tract
PRST
excites extensors
p plus
medullary reticulospinal tract
MRST
inhibits extensors
M minus
Central tegmental tract
consciousness
medial forebrain bundle
pleasure pathway
cholinergic
nucleus basalis of meynertt
septal nuclei
inactivation of monamines
monoamine oxidase
reuptake
noradrenergic neurons
mood, memory, hormones
lateral tegmental group
locus coeruleus
dopaminergic neurons
nigrostriatal path
mesocorticolimbic path
tuberoinfundibular path
serotonin
made in raphe nuclei
decerebrate posturing
lesion btwn rostral red nucleas and mid pons
upper and lower limbs extedned spasticiity
decorticate postureing
diencephalon
upper limb flexion (red nucleus intact)
lower limb extension
midpontine RF
turns on exctitatory neurons
promotes wakefulness
RF in caudal pons
turns off excitation from mid ponitne
posterior hypo
hypersomnia
anterioro hypo
hyposomnia
sleep cycle
awake
SS1,2,3,4
Rem
REM sleep
rapid eye movement
paradoxical sleep because loud wont wake u but whispered name will
suprachiasmatic nucleus
regulates circadian rythm
acetylcholine
wakefullnesss and rem sleep
basal forbrain
laterodorsal and pedunculo pontine tegmental nuclei
norephinephrine
locus coeruleus
fight or flight
wakefulness
histamine
tuberomammilary nucleus of posterior hypothalamus
wakefulness
serotonin 5-HT
raphe nuclei
wakefulness
dopamine
substantia nigra
wakefulness
orexin hypocretein
OX
lateral hypothalamus
wakefulness
flip flop system for sleep wake transitions
Ventrolateral preoptic area
GABAergic neurons that suppress wakefullnes neuromodulators
GABA and glycine
REM
during REM they inhibit a lot and eliminate muscle tone
ACetylcholine in REM
only thing not turned off in REM
from basal forebrain and pons to cortex
flip flop system
Orexin turnes on awake stuff which turns off asleep stuff
asleep stuff turns off both the others
imagine a scale when one gets too high it swaps
sublaterodorsal nucleus
ventral part of the periaqueductal gray in the lateral ponting tegmentum and chollinergic nuclei
pontine circuit of REM sleep
insomnia and narcolepsy
unstable flip flop switch
somnambulism
sleep walking
stuck between non rem and wake stage
sympathetic
fight or flight
info from throaci and lumbar cord
ganglia close to spinal cord
parasympathetic
rest digest
info from brainstem and sacral cord
close to organs
reflexes ans vs sns
hypothalamus vs somatosensory and motor cortex
RVLM
rostral ventrolateral medulla
glutamate gaba epinephrine
supraspinal vasomotor pathway thru dorsolateral funiculus
spinal shock
acut sci
transient
abesnt of voluntary and reflex below injury
neurogenic shock
30min to 6 weeks
hypotension
bradycardia
poikilothermia
injurey below T6
maintain blood pressure
injury above T6
lose control of BP and heart rate
orthostatic hypotenison
drop in blood pressure with 90degree head up tilt
acute: loss of vasomotor tone
chronic” reduced sympathetic activity
autonomic dysreflexia
sudden episod high blood pressure
baroreflex mediated bradycardia
T6 or higher
lose inhibitive cortical input responding to sympathtetic response from full bladder
spinal plasticity response to cardiovascular abnormality
CGRP+ cfiber afferents density increases
Nerve growth factor
propriospinal sprouting
gabapentin
decreases presynaptic glutamate release
suppresses muscular spasticity and neuropathic pain
lower urinary tract
external urethral spicnter has somatic nerves
othersr are autonomic
supraspinal mictuition
barringtons nucleus
periaqueductal gray
nucleus tractus solitarri
micturition pathways
spinal reflexes for storage
spinobulbospinal relexes for voiding
detrusor sphincter dyssynergia
loss of recipercot relationship
molecular changes after sci
NGF up
primary c fiber afferent sprouting up
GDNF BDNF and NT3 up
treatments
E stim of pudendal nerve
PNGs
Lateral geniculate nucleus
eyes
medial geniculate nucleus
auditory
Ventral posterior laterall nucleus VPL
body
VPM
face
ventral posterior inferior nucleus VPI
vestibular info
right visual field
left side of brain
after chiasm
defecits in contra visual field
effects both eyes
damage in one retina
scotoma monocuolar
that specific visual filed affected
lesion of opitc nerve
loss from one eye visual field
leaseon of optic chiasm
nasal retina cross
temporal dont
hemianopia bitemporal
so temporal visual field loss cuz nasal retina lost?
lesion of optic tract or lateral geniculate
contralateral visual
superior bank
inferior visual field
pupillary light refelx
each pretectal nuclei gets input from both sides and sends to both edingerwestphal and goes to constrict
blind in right eye pupilary reflix
right eye nothing
left eye response in both sides
if only one eye responds then motor pathway is damaged