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Pharmacology > MECHANISMS OF SIGNAL TRANSDUCTION IN ADRENERGIC RECEPTORS > Flashcards

MECHANISMS OF SIGNAL TRANSDUCTION IN ADRENERGIC RECEPTORS Flashcards

1
Q

Alpha1 adrenoceptors

A

Gq proteins activating phospholipase C,

which contribute to formation of diacylglycerol (DAG) and inositoltriphosphate (IP3)

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2
Q

Alpha 2 adrenoceptors

A

– Gi proteins, which inhibit adenylyl cyclase

leading to decrease of intracellular cAMP

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3
Q

Beta adrenoceptors

A

– Gs proteins, which stimulate adenylyl cyclase

leading to increase of intracellular cAMP

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Pharmacology (12 decks)

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