May Flashcards
What is the age range for OTC use of acrivastine products?
12-65 years
What is the age range for OTC buscopan cramps?
6 years plus
What is the age range for OTC Zantac (ranitidine)?
16+
What is the age range for Eumovate cream OTC? what is the active?
Clobetasone 0.05%, 12+ up to 7 days.
What drugs can cause QT prolongation?
Hydroyzine Macrolides Quinine SSRIs (Not exhaustive list)
What is the mechanism of action of alogliptin?
DPP4 inhibitor
What is otezla?
Apremilast: used for psoriasis and psoriatic arthritis alone or in combination with DMARDS
What is porsalen?
Furocoumarin used with UVA to treat psoriasis, eczema, vertiligo and cutaneous T-cell lymphoma.
What is Co-tenidone?
Atenolol and chlortalidone
What is the age range of montelukast chewable 4mg tablets?
6-14
What is slapped cheek caused by?
Virus
What is scarlett fever caused by?
Bacteria
What STI does ofloxacin treat?
chlamydia and gonorrhoea
What is the normal sodium level?
135mmol/L
Why is propylene glycol a problem excipient in the young?
It is a solvent but can cause CNS effects in neonates and those younger than 4.
Polyoxyl castor oil has been associated with what in children?
Severe anaphylactoid reactions
Polysorbate 80 can cause what syndrome?
E-ferol syndrome - toxic syndrome associated with intravenous vitamin E prep with polysorbate 80.
Benzyl alcohol, used as a pharmaceutical preservative can cause what syndrome in the very young?
Gasping syndrome:
A syndrome in preterm neonates exposed to benzyl alcohol preservative in intravascular solutions that is characterized by unremitting gasping respirations and may include anion gap metabolic acidosis, neurologic deterioration, renal failure, convulsions, intraventricular hemorrhage, and cardiovascular collapse.
Benzoic acid, a preservative, is associated with what in neonates?
Jaundice.
Parabens used as preservatives are associated with what effects?
Oestrogenic effects
Benzalkonium has been associated with what when used with anti-asthmatic drugs?
Bronchospasm
What is quinagolide? What does it treat?
Quinagolide is a selective D2 receptor agonist that is used to reduce elevated levels of prolactin - treating breast pain.
What is eltrombopag? what does it treat?
It is a small molecule agonist of the c-mpl receptor, the physiological target of the hormone thrombopoetin.
It is used to treat conditions that lead to thrombocytopeania.
