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Random (Pre-Reg) > April > Flashcards

April Flashcards

1
Q

Gradual withdrawal of systemic corticosteroids should be considered if a patient has received what level of Prednisolone over what length of time?

A

At least 40mg prednisolone daily for more than 1 week

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2
Q

With lithium monitoring, plasma lithium levels should be taken how long after the last dose?

A

12 hours

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3
Q

How does glimepiride work?

A

A sulphonylurea that stimulates the production of insulin in pancreatic islet cells

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4
Q

Why should bismuth subsalicylate not be used in under 16?

A

Think aspirin, salicylate, Reye’s syndrome

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5
Q

What are black triangle drugs?

A

Newly licensed drugs that are monitored intensively by the MHRA

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6
Q

Crohn’s disease normally affects what part of the gastro-intestinal tract?

A

Can affect any part of it

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7
Q 
Azathioprine interacts with:
Allopurinol 
Morphine 
Atenolol 
Gabapentin
A

Allopurinol

Increased risk of toxicity when allopurinol and azathioprine given together

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8
Q

Records concerning the destruction of schedule 2 drugs should be kept for how long?

A

7 years

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9
Q 
There is an increased risk of myopathy when simvastatin is given with:
Ranitidine 
Verapamil 
Warfarin
Azathioprine
A

Verapamil

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10
Q 
Which of the following are not used in depression?
Citalopram 
Amitriptyline
Phenelzine
Nefopam
A

Nefopam is not used in the treatment of depression.

Pain medicine

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11
Q

Atenolol is one of the most water soluble beta-blockers. What impact does this have on its ability to cause sleep disturbances?

A

More water soluble = less likely to cross blood brain barrier = less likely to cause sleep disturbance

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12
Q

What type of insulin is isophane insulin?

A

Intermediate acting

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13
Q

How is doxycycline used for malaria prophylaxis?

A

1-2 days before entering malaria area, duration of stay and for 4 weeks afterwards

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14
Q 
There is an increased risk of myopathy when simvastatin is used with:
Lithium 
Grapefruit juice 
Colchicine 
Amlodipine
A

Increased risk of myopathy when with grapefruit juice, amlodipine and colchicine.

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15
Q

A woman is considered fertile for how long after her last period?

A

2 years if under 50, 1 year if over 50

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16
Q 
Which of the following is not a type of psoriasis:
Chronic plaque psoriasis 
Guttate psoriasis 
Psoriasis of the nails
Arhritic psoriasis 
Epidermal psoriasis
A

Epidermal psoriasis.

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17
Q 
Which of the following is not a sign of chronic renal failure?
Pruritis
Yellowing of the skin and iris
Bruising
Anorexia
Peripheral neuropathy
A

Yellowing of the skin and iris = jaundice = liver failure

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18
Q 
Which of the following is not a function of the liver:
Storage of bile
Filtration of waste products
Metabolism
Synthesis of proteins 
Homeostasis
A

Storage of bile

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19
Q 
Which of the following causes GORD:
Smoking
Diet rich in fibre
Drugs such as H2 receptor antagonists
Drugs such as H1 receptor antagonists 
Diet rich in protein
A

Smoking

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20
Q

Leafy greens have what effect on INR?

A

Decrease it, warfarin prevents the production of vitamin k-dependent clotting factors. Green, leafy vegetables are rich in vitamin K.

21
Q

Dietary supplementation of which vitamin should be avoided by pregnant women?

A

A, or retinol, can harm the growth of a fetus

22
Q 
Which of the following tests is not currently routinely recommended before starting treatment with amiodarone?
Liver function test
Chest X-ray
Thyroid function test 
Kidney function test
A

CXR, LFTs and TFTs should be completed every 6 months for patients taking amiodarone.

23
Q 
Which of the following beta-blockers are not cardioselective?
Bisoprolol
Atenolol
Nebivolol
Propranolol
A

Propranolol is not cardioselective, the other three are.

24
Q

In anaphylaxis, how often should adrenaline injections be administered if symptoms remain/recur?

A

Every 5 minutes.

25
Q

How long until senna works?

A

8 hours

26
Q

A foul, fishy-smelling discharge indicates what GU condition?

A

Bacterial vaginosis

27
Q

What is the treatment of bacterial vaginosis?

A

Oral metronidazole:
Suggested duration of treatment 5–7 days (or high-dose metronidazole as a single dose).

Alternatively, topical metronidazole for 5 days or topical clindamycin for 7 days

28
Q

Hydrocortisone 0.1% cream can only be sold for use by patients that are at least how old?

A

10 years of age

29
Q

What is first-line treatment for indigestion?

A

Antacids such as magnesium hydroxide.

30
Q

Long term use of proton pump inhibitors has been associated with increased risk of what GI condition?

A

C. difficile

31
Q 
Which of the following has faecal softening activity?
Docusate sodium
Bisacodyl
Senna
Isphagula husk
A

Docusate sodium is a stimulant laxative with faecal softening activity.

Bisacodyl is a stimulant laxative.

Senna is a stimulant laxative.

Isphagula is a bulk forming laxative

32
Q

What is an FP10CDF form used for?

A

Requisitions for sch 2 or 3 CDs

33
Q

Which of the following antimicrobials has a significant interaction with azathioprine?

Trimethoprim
Metronidazole
Oxytetracycline
Fluconazole

A

Azathioprine and trimethoprim = increased risk of toxicity

34
Q

Can senna be used safely in pregnancy?

A

No it is a stimulant laxative

35
Q

What is the treatment of whooping cough in infants less than 1 month of age?

A

Clarithromycin

36
Q

What is the treatment of whooping cough in children aged 1 month or older and non-pregnant adults?

A

Azithromycin or clarithromycin

37
Q

What is the treatment of whooping cough in pregnant women?

A

Erythromycin for pregnant women from 36 weeks gestation

38
Q

Can clarithryomycin be used with:

a) haloperidol
b) sotalol
c) terfenadine
d) pimozide

A

None of them, they all prolong QT intervals and so can macrolides.

39
Q

Are macrolides safe to use in liver failure?

A

No, excreted mainly by the liver

40
Q

Ursodeoxycholic Acid is contraindicated in patients with what?

A

Ursodeoxycholic Acid is contraindicated in patients with acute inflammation of the gall bladder

41
Q

Which illness is characterised by white spots surrounded by a red ring on the inner cheek and gums?

A

Measles

42
Q

Vaccination against this disease is usually given within the first year of life in a combination vaccine with diphtheria, tetanus, haemophilus influenza type b and polio.

A

Whooping cough

43
Q

Pregnant women have to be extra cautious to ensure that they will not come into contact with this disease as there is an increased risk of congenital abnormalities?

A

German measles: rubella

44
Q

What temperature should pharmacy fridges be maintained between?

A

2-8*C

45
Q

What medicines should be taken in the morning and on an empty stomach?

A

Levothyroxine, lansoprazole and perindopril.

46
Q

What medicines should be taken after food?

A

Metformin, NSAIDs, nitrofurantoin (or with).

47
Q

What medications should be taken with food?

A

Bulk forming laxatixes (and 300ml).

Aldosterone antagonists

Metformin (With or after)

Nitrofurantoin (or after food)

48
Q

Can ACEi, gabapentin and phenytoin be given with antacids?

A

NO

Random (Pre-Reg) (11 decks)

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