May 16 Flashcards
Ischemic infarct CT appearance
Hypodense, poorly delinieated
Edema, loss of grey/white matter distinction
Infarct course
During first 48 hours, red neurons.
Neutrophils move in, then microglia (macrophage).
Microglia stain the strongest as fat cells. (Break down stuff, cause of liquefactive necrosis)
Acute decompensated heart failure in CXR
Cardiomegaly
Secondary pulmonary edema (kerly b lines).
Perihilar alveolar edema (batwing)
Path of CSF flow
Choroid plexus secretes, lateral ventricle->interventricular foramen of monro -> third ventricle -> cerebral aqueduct -> fourth ventricle -> foramina of Luschka and Magendie -> subarachnoid space.
Absorbed y arachnoid granulations into venous sinus.
DSM5 for tourette
Multiple motor and one+ vocal tic (not necessarily concurrent)
>1 year.
Before 8
Treat with: antipsychitics, alpha-receptor antagonist, therapy
Filtration Fraction
FF = GFR/ RPF
GFR: creatnine.
RPF: PAH.
Clearance (urine X flow / serum).
Consequence of giardiasis
Lactose intolerance (lactase deficiency) Lactose -> Galactose
Projection
Misattributing one’s own feelings to another who doesnt have them.
I lost the game. They must be ashamed of me (when really I’m ashamed).
TNF-alpha inhibitors
Adalimumab, infliximab, etanercept.
G6PD
X linked
Rate limiting in Pentose Phosphate (Glucose -6- phosphate to 6-phpsphogloconate (creating NADPH).
Oxidative damage causes hemolysis. (TMP/SMX for UTI can cause)
Acidos/alkalosis compensaton
Met Acid: pH down, pCO2 down (HyperVent), HCO3 down.
Resp Acid: pH down, pCo2 Up, HCO3 up.
Met Alk: pH up, pCO2 up, HCO3 up.
Resp alk: pH up, pCO2 down, HCO3 down.
Ankylosing spondylitis
Low back pain, improves with exercise but not rest (pain at night).
Hip, butt.
Limited chest expansion, chest mobility.
Systemic issues (fever, chills).
B27
Foot drop
Mostly common peroneal nerve
How is isoniazid metablized?
Liver. Acetylation (phase II)
Also: procainamide, hydralazine, TNF-alpha inhibitors.
Epinephrine effects
Alpha 1= vascular smooth muscle. VasoC.
Beta 1= skeletal smooth muscle. VasoD. increase heart rate.
If high dose, alpha 1 predominate, increased BP. If low, beta2 = decreased blood pressure.
Which HIV gene is related to rsistance to drugs?
Pol = to reverse transcriptase inhibitor and protease inhibtor
ENV: to escape antibodies (capsule).