May 14: Fat Soluble Vitamins Flashcards
Vitamin D function
Calcium metabolism:
Calcium absorption
Regulation of blood calcium levels (kidneys)
Bone mineralization by maintaining calcium concentrations
What are some possible additional functions of vitamin D?
Possibly cancer prevention?
(Low circulating vitamin D linked to increased cancer risk)
Protection against cardiovascular disease and hypertension
Prevention of autoimmune diseases
Where is vitamin D deficiency a problem?
It is a problem in areas with reduced exposure to sunlight
What can vitamin D deficiency cause?
Rickets in children
Overgrowth of cartilage
Enlarged head
Rickets
Soft bones
How can vitamin D need be met?
Through 30 minutes to 2 hours of daily sunlight exposure
RDA for vitamin D
600 IU (international units) for ages 1-70
800 IU for 70+ age
Food sources of vitamin D
Fatty fish, fortified milk, mushrooms (grown under UV light)
Vitamin D toxicity
2-3 times the RDA is toxic to children
Vitamin A function
Vision cycle - ability to perceive black/gray/white/night vision
Maintenance of epithelial tissue (“covering tissue”)
Vitamin A deficiency
Can cause night blindness, xerophthalmia, infection
Xerophthalmia
Cornea sloughs off, causing blindness
500,000 children < 5 years old go blind yearly due to vitamin A deficiency
Food sources of vitamin A
Animal sources, beta carotene (any green, orange, or red fruit/veg. This is converted to vitamin A)
What if you eat too much beta carotene or vitamin A?
Beta carotene isn’t toxic so this isn’t a problem; it acts as an antioxidant
However, vitamin A can be toxic. It is stored in the liver and excess can lead to birth defects, enlarged liver
Vitamin E function
Antioxidant: protects cell membranes from oxidation
Prevents lipid “peroxidation”