Maternal Physiology Flashcards

0
Q

Uterus

Week 12

A

Abdominal organ
Dextrorotation
Isthmus enlargement and thinning

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1
Q

Softening and compressibility of the isthmus occurring on the 6th to 8th w AOG

A

Hegar’s sign

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2
Q

Softening of cervix pronounced on 6th to 8th wk AOG

A

Goodell’s sign

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3
Q

Poor pap smear quality during pregnancy

A

Arias Stella reaction

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4
Q

Bluish or purplish discoloration of vagina at 6 w AOG

A

Chadwick’s sign

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5
Q

Cervical mucous changes

Vaginal secretion changes

A

Crystallization or beading

Acidic

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6
Q

T or F

Montgomery glands of the breast increase in size starting the 3rd month of pregnancy

A

2nd

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14
Q

Melanocyte Stimulating Hormone effects

A

Linea nigra
Darkening of the areola
Chloasma or melasma

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15
Q

Hyperestrogenemia

A

Spider nevi

Palmar erythema

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16
Q

Corticosteroids

A

Striae gravidarum at breast and abdomen

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17
Q

Water metabolism

A

Inc water retention

Fall in plasma osmolality

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18
Q

Protein metabolism

A

+500g fetus and placenta

+500g uterus breast blood

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19
Q

CHO metabolism

A

Periph insulin resistance
Mild fasting hypoglycemia
Postprandial hyperglycemia

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20
Q

Resets lipostat in hypothalamus causing hyperlipidemia

A

Progesterone

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21
Q

Na and K
Ca and Mg
Fe

A

Inc: Enhanced tubular reabsorption of Na and K
Dec: Total calcium levels decline but ionized ca is unchanged
100 mg requirement

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22
Q

Weight gain
First trimester
2nd
3rd

A

2
11
11

23
Q

Hypercoaguable state

All coag factors inc except

A

11 and 13

24
Q

Dec in CBC

A

Hematocrit

Platelets

25
Q

Ocular changes

A

Dec IOP inc vitreous outflow
Dec corneal sensitivity
Inc corneal thickness edema

26
Q

Skeletal changes

A

Progressive lordosis

Inc mobility of pelvic joints

27
Q

Pulmonary changes

A

TV and Resting minute ventilation inc

FRC and RV dec due to elevation of diaphragm

28
Q

ABG

A

Relative alkalosis

Blowing off more CO2 than nonpregnant

29
Q

Cardiac changes

A
HR + 10 bpm
Inc plasma volume by 40-60
Inc CO by 30-40
Dec DBP TPR
Inc venous pressure in LE
30
Q

Periods of inc CO

A

28 w
Labor
Postpartum
1st week pp

31
Q

GUT changes

A

Urinary stasis Asx bacteriuria
Freqency and nocturia
Hydroureter

32
Q

Renal changes

A

Inc GFR by 50% RPF Clcr

Dec serum BUN Crea UA

33
Q

GIT changes

A

Appendix displaced downward and laterally
Inc gastric emptying time and
Dec LES tone causing heart burn
Progesterone inhibits CCK causing cholelithiasis and pancreatitis
Estrogen inhibits bile acid transmission to GB causing pruritus
Epulis

34
Q

Endocrine changes

A

Pituitary gland enlarges by 135%
Inc prolactin and oxytocin
Adrenal and thyroid hyperplasia

35
Q

Immunologic changes

A

Inc WBC IgA IgG

Dec T helper cells and neutrophils