Female And Reproductive Physiology Flashcards
Receptors
Granulosa
Theca
FSH
LH
Functional unit of the ovary
Ovarian follicle
Primary oocyte
Arrested in
from
Until
Prophase
5th fetal month
Puberty
Secondary oocyte
Arrested in
From
Until
Metaphase II
Ovulation
Fertilization
Menstruation
Myometrial contractility
Prostaglandin F
Two cell hypothesis
Follicular phase
LH stimulates desmolase in thecal cells to produce androgens
FSH stimulates conversion of androgen to estradiol in granulosa cells
Estrogen effects
Uterus
Cervical mucous
Proliferative phase
Thin and watery, ferning
LH surge
Ovulation
Release of cumulus oocyte complex
Luteinization of granulosa cells
Remains of Graafian follicle becomes corpus hemorrhagicum maturing into corpus luteum (progesterone)
Luteinizaton
Cause mitterschmerz or mid cycle pain
Corpus hemorrhagicun
Progesterone effects
Uterus
Cervical mucus
Systemic
Secretory, subnucleolar vacuoles
Thick
Thermogenic, inc water retention
Key to initiation if ECM breakdown of stratum functionalis
Neutrophilic infiltration
IL8
Earliest histo logical evidence of progesterone action
Basal vacuolation
Most abundant histologic marker during proliferative phase
Stromal mitoses
Constant phase of menstrual cycle
Post ovulatory
Luteal
Secretory
14
Dominant hormone
Pre ovulatory
Post
Estrogen from granulosa
Progesterone from luteum
Highly modified endometrium of pregnancy
Decidua
Decidual layers
Basalis beneath blastocyst implantation unresponsive
Capsularis chorion 2nd month obliterated by growing fetus
Parietalis responsive to vasoactive agents
Post conception week 1
Cleavage
Morula (ICM and OCM) which enters uterus at day 3
Blastocyst (embryoblast and trophoblast)
Implantation at post sup functional layer of uterus
Post conception week 2
Bilaminar embryonic disk: epiblast to amniotic cavity and hypoblast to yolk sac
Mitotically active cytotrophoblast and secretory syncitiotrophoblast (HCG)
Post conception week 3-8
Teratogen susceptibility
Ectoderm Endoderm Mesoderm
Completed by week 8
Heart
UE LE
Upper lip
Completed by week 9
Ext genitalia
Folate acid
Normal
Prior child with N
Epileptic
400 mcg
4 mg
4 mg
Anomalies
Embryonic period
Fetal period
Major congenital anomalies
Functional/growth retardation
Fetal to maternal membranes
Amnion avascular Chorion Decidua parietalis Myometrium Serosa
