Hypertensive Disorders Flashcards
Main pathogenesis of GH
Vasospasm and endothelial cell activation
Most impt RF for GH
Nulliparity
Exposure to chorionic villi for the first time
Most consistent anatomical finding of HPN in pregnancy
Glomerular Capillary Endotheliosis
Pathognomonic lesion in eclampsia
Periportal Hemorrhagic Necrosis
Most common cerebral finding in GH
Edema
MC hematologic abnormality in GH
Thrombocytopenia
Hallmark placental lesion
Acute atherosis of decidual arteries
Doppler velocimetry GH
Diastolic notch in uterine artery
Absent or reversed end diastolic blood flow in umbilical artery (most ominous)
Prophylaxis for eclampsia
MgSO4
MgSO4 levels 4-7 10 12 30
Tx
Loss of patellar reflexes
Respiratory paralysis
Cardiac arrest
Urgent control of severe pre eclampsia
Labetalol Hydralazine Clonidine Nifedipine Nicardipine
DOC maintenance drug for GH
Methyldopa
Labetolol