masterclass 3 Flashcards

1
Q

lithium carbonate is used for

A

mania and prophylaxis of manic depression

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

how does lithium work

A

substitutes for sodium or potassium in the CNS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

bad thing about lithium

A

narrow therapeutic index

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

drugs with narrow therapeutic window

A

warfarin, gentamicin, digoxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

volume of distribution

A

amount of a drug in the body divided by the amount of plasma concentration

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

half life of 24 hours, how many days to get steady state

A

5 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what to do to make sure lithium isnt toxic

A

regular blood tests

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

what types of relief does lithium have

A

standard and modified release formulations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

IV drugs bioavailability

A

100%

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what has higher bioavailability oral or IV

A

IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

important about lithium prescribing

A

prescribe by brand

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

how long does it take for digoxin to reach steady state

A

6 days

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

how to get to a steady state faster

A

loading dose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

where can digoxin accumulate

A

muscle

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what are the two formulations of digoxin

A

tablet

liquid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly