masterclass 3 Flashcards
lithium carbonate is used for
mania and prophylaxis of manic depression
how does lithium work
substitutes for sodium or potassium in the CNS
bad thing about lithium
narrow therapeutic index
drugs with narrow therapeutic window
warfarin, gentamicin, digoxin
volume of distribution
amount of a drug in the body divided by the amount of plasma concentration
half life of 24 hours, how many days to get steady state
5 days
what to do to make sure lithium isnt toxic
regular blood tests
what types of relief does lithium have
standard and modified release formulations
IV drugs bioavailability
100%
what has higher bioavailability oral or IV
IV
important about lithium prescribing
prescribe by brand
how long does it take for digoxin to reach steady state
6 days
how to get to a steady state faster
loading dose
where can digoxin accumulate
muscle
what are the two formulations of digoxin
tablet
liquid