Marijuana Flashcards
5 types of THC containing classes
“Low grade” weed, “mid grade” weed, sinsemilla, hasish, hasish oil
Where is low grade weed found and what’s its THC content?
Leaves of male and female plants, 1-2%
Where is mid grade weed found and what’s its THC content?
Fertilized flowers of female plants, 2-5%
Where is sinsemilla found and what’s its THC content?
Non fertilized female buds, 8-15%
Where is hashish found and whats its THC content?
Dark and gummy resin from c. sativa, 8-14%
Where is hash oil found and what’s its THC content?
Boil c. sativa in alcohol then evaporate it, makes an oil. 15-60%
During which significant era did marijuana use peak?
Prohibition
When was marijuana first used?
3000BC China - India
What act was enacted in 1937 to try to decrease marijuana use?
1937 Marijuana Tax Act
Define decriminalized in terms of marijuana
Weed isn’t really legal but the police will leave smokers alone if they aren’t being bothersome
Difference in onset b/w inhalation and oral marijuana use
Smoking: minutes
Oral: 1hr ish
Difference in peak symptoms b/w inhalation and oral use of marijuana
Smoking: 15-60 mins
Oral: 2-3hrs
Difference in duration b/w smoking and oral use of marijuana
Smoking: 2-4hrs
Oral: 4-6hrs
3 different inhalation options and their THC content
Joint: 20-50% THC
Pipe: 40-50% THC
Water pipe/bong: 80-90% THC
What drug has high lipid solubility?
Marijuana
Which organ excretes THC?
Kidneys
Which organ metabolizes THC?
Liver
How long can marijuana metabolites remain in the system?
30 days
Medicinal uses of THC
- anti nausea and increases appetite for chemo patients and AIDS patients
- can decrease anxiety
Parts of the brain affected by THC and the effects
Cerebellum: motor performance disrupted
Hippocampus: low concentration and no concept of time
Basal ganglia: low motor activity
FC: sense distorted
DA pathway: mild euphoria
Hypothalamus: increased appetite
Vasodilation: increased HR, blood shot eyes
What did the THC treated rat do differently?
- showed higher pain tolerance on hot plate
- stayed hung on catalepsy bar longer (heavy limbs)
- much more relaxed
2 endocanabannoids
Anandamide and 2AG
Does the route of admin affect withdrawal symptoms?
No
