CH 9: Alcohol Flashcards

1
Q

How is alcohol made? AKA what is the formula?

A

Carbohydrates + yeast = ethanol

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2
Q

3 major classes of alcohol

A

Beer, distilled spirits, and wines

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3
Q

What is beer made from and what’s its alcohol %?

A

Grains, 3-8%

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4
Q

What is wine made from and what’s its alcohol %?

A

Grapes, 10-15%

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5
Q

What kind of product are distilled spirits and what’s its alcohol %?

A

Fermented, 30-50%

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6
Q

What is proof?

A

2x the alcohol %. Ex: 50% alcohol = 100 proof

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7
Q

What’s the highest proof?

A

Everclear, 190

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8
Q

Is alcohol found in nature?

A

Yes, fermented apples and the marula fruit

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9
Q

What does the rate of alcohol absorption depend on?

A

-volume -type of alc -rate of consumption -food -gastric metabolism

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10
Q

Where is alcohol metabolized?

A

Primarily liver, stomach, some by kidney and lungs

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11
Q

At what rate does the liver metabolize alcohol?

A

0.35oz/hour

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12
Q

What is the metabolic process of alcohol breakdown?

A

Alcohol -(alc. dehydrogenase)-> acetaldehyde -(acetaldehyde dehydrogenase)-> H20 +CO2+NRG

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13
Q

Why is ALDH so important?

A

Because acetaldehyde is a carcinogen, if it builds up this can lead to not only hangovers but also cancer

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14
Q

Why does alcohol make us pee?

A

It’s a diarrhetic

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15
Q

What is antabuse?

A

A pill that causes acetaldehyde buildup when consuming alcohol. Makes the individual very sick and causes hopefully conditioned taste aversion to help alcoholics steer clear from alc

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16
Q

What is first pass metabolism?

A

When the drug concentration is greatly reduced before it is circulated through the body

17
Q

What is alcohol absorbed by and where is it sent?

A

Small intestine into the blood

18
Q

Which sex metabolizes alcohol faster and why?

A

Men because they have higher levels of ADH in their stomach than women

19
Q

What are the 2 cellular mechanisms of action of alcohol?

A
  1. alcohol crosses all cell membranes and interferes with neuron firing
  2. affects all NT but mainly increases GABA