march 9th Flashcards
What is the calculation for respiratory compensation during metabolic alkalosis?
.7*Hc03- + 20 +/-5
< .7*HCo3- + 44
What is the triad for lead colic?
Intermittent vomiting
Abdominal pain
Colic
What is the rate limiting step in heme synthesis?
Aminolevulinate synthetase
By what two mechanisms does lead poisoning affect heme synthesis?
Inhibitts Ferrochelase
Inhibits aminolevulinate dedratase
What is the function of ferrochelase?
Binds iron with Protoporphyrin to make heme
- last step in the synthesis
Pt is born with a cleft lip. What sort of problems will they have? Especially during feeding?
They cannot create the suction needed to feed. Thus they choke, spit up and cough. They have poor weight gain right away. There are no other facial abnormalities or any other systemic systems
What is the mnemonic for microtubules inhibitors?
Microtubules Get Constructed Very Poorly Mebendazole Griseofulvin Colchocine Vincristine Paxiltaxel
What are the atypical pneumonias?
Mycoplasma
Legionella
Chlamydia
What are the nosocomial pneumonias?
S aureus
Pseudomonas
Gram - rods
What are the post viral pneumonias?
Strep Pneumoniae
S. Aureus
H Flu
What causes psittacosis? How does one get it?
Chlamydophila psittaci
caused by parrot droppings
You suspect someone has psittacosis. You RX what and who should you call, besides ghost busters?
Doxyclycine/other tetracycline
- State public health service
What is the MOA of amantidine?
Increase dopamine release and prevent reuptake
What is amantidine used for?
Parkinson’s
Influenza/Rubella
What are the adverse affects of amantidine?
Ataxia Dizziness Slurred speech Psychosis Livido Reticularis (skin lace like purpurlish discoloratio)
What do HIV pts with Bartonella infection get?
Bacillary angiomatosis
Does men having sex with me increase your chances of getting giardia?
yes
What is a common vector of histoplasmosis?
Bat and bird droppings
What are roth spots and what disease are they found?
They are seen in acute endocarditis. They are white spots on retina surrounded by hemorrhage.
What are the causes of acute endocarditis?
Viradans
What are the strains of strep Viradans?
Mutans
Sanguinis
Oralis
Mitis
What vessel do nitros affect more?
Veins
- Thus decrease in preload which decreases the O2 demand of the heart
At low doses what do nitros affect more? How about high doses?
Veins at low doses
- both at high doses
What bring on angina with stable angina pectoris?
Things that increase the O2 demand of the heart
- exercise
- emotional stress
- cold
These are relieved at rest
Abx in a strep infection protect against what? What does it not protect against?
Rheumatic fever
-not against PSGN
What abnormality happens in 99% of the cases of rheumatic fever?
Mitral stenosis
