March 10th Flashcards

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1
Q

what is the mnemonic for the brachial pouches, arches and clefts? What are they derived fro?

A

CAP–> outside to inside

  1. Clefts–> ectoderm
  2. Arches–> mesoderm and neural crest cells
  3. Pouches–> endoderm
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2
Q

What do the brachial arches give rise to?

A

mesoderm–> gives rise to the muscle and arteries

Neural crest cells–> give rise to the neurons

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3
Q

What does the 6th brachial arch give rise to?

A

All intrinsic muscles of the larynx except for the cricothyroid

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4
Q

What innervates all the intrinsic muscles of the larynx?

A

Recurrent laryngeal

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5
Q

What is more common bones mets or primary bone cancer? What are the primary bone cancers?

A

Mets

- Multiple myeloma and Lytic

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6
Q

Pt has bone mets from what location cause lytic lesions?

A

Thryoid

Kidney

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7
Q

What bone mets cause mixed lytic and blastic lesions?

A

Breast

Lung

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8
Q

Male who is 85 years old. What is the class blastic bone mets original cancer location?

A

Prostate

- the most common bone mets cancer

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9
Q

what are the most common causes of bone mets?

A

Prostate
Breast
Lung
RCC

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10
Q

elderly pt presents a Posterior hip dislocation. What nerve is commonly involved and what actions should the pt have trouble with?

A

Inferior gluteal nerve

  • problems standing from sitting
  • Trouble climbing stairs
  • trouble jumping
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11
Q

Why does a pt with problems of the inferior gluteal have troubles standing from sitting, climbing stairs or jumping?

A

Glut max is a powerful hip extensor

- hip extension is required for all of these actions

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12
Q

What activates CDK’s?

A

Cyclins

hense cdk= cyclin DEPENDENT kisases

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13
Q

what is the most common no-hematopoietic cancer?

A

Osteosarcoma

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14
Q

How can one differetiate between photosensitivity and stevens-johnson syndrome?

A

SJS has 2 or more mucous membranes involved

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15
Q

What drugs are more common to cause SJS or TENs?

A

Allopurinol
Lamotrigine
Sulfonamides
Navirapine

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16
Q

What other diseases resemble SJS?

A

HSV

Mycoplasma in children

17
Q

Pts has very bad acne vulgaris. What is the common RX?

A

Tetracyclines

18
Q

What else do tetracyclines act against?

A
Rickesial 
Cholera
Lyme dz
Mycoplasma
Chlamydia
19
Q

What muscles does the radial nerve innervate?

A

BEST

  • Brachioradialis
  • Extensors + aBductor pollicis longus
  • supinator
  • Triceps
20
Q

What increases your chances of tendon rupture from flouroquinolones?

A
>60 years old 
Renal transplant
Renal failure
Hemodialysis
Long term glucocoritcoids
21
Q

Pts comes to office with tender muscular and soft mass at the proximal calf. He is having extreme pain of the right ankle and difficulty walking and plantarflexion. Likely DX if hes on abx’s?

A

Achilles tendon rupture

22
Q

What metabolizes 6-Mercaptopurine?

A

Xanthine oxidase

23
Q

Thus what increases the toxic motabolite of azathioprine?

A

Xanthine oxidase inhibitors

  • Allopurinol
  • Febuxostat
24
Q

If one were to take both allopurinol and Azathioprine , what would be the unfavorable SE?

A

Aplastic anemia

25
Q

What nerve innervates the adductor pollicis?

A

Ulnar nerve

26
Q

What is Froment sign?

A

Pt has a palsy in the ulnar nerve. They recruit their flexor pollicis to try old a piece of paper with their thumb and index rather than adduction of the thumb

27
Q

Young pt comes to office with short stature and large head. He has a mutation in FGFR3. What is the disease and what is it associated with?

A

Achondroplasia

ass. with advanced paternal age