feb 23rd

Question 1

What two things account for approx 1/2 of all hospital acquired infections?

Answer 1

In dwelling catheters

Surgical site infections

Question 2

How does carcinoid syndrome lead to diarrhea?

Answer 2

Increase peristalsis

Question 3

What is used to treat Carcinoid syndrome? How? What other sx’s does it help?

Answer 3

Octreotide

• acts to inhibit the release of serotonin from the carcinoid tumor
• also affecting in decreasing flushing and diarrhea

Question 4

What are the heart sx’s in carcinoid syndrome? Why is that affected only?

Answer 4

Tricuspid stenosis/ regurg
Pulmonic stenosis
- only affects left because the lung inactivate serotonin

Question 5

What is the break down of serotonin found in the urine?

Answer 5

5 Hydroxyindoleacetic acid

- 5-HIAA

Question 6

What is the most common inflammatory diarrhea in the US?

Answer 6

Campylobacter jejuni

Question 7

what are the two locations of synthesis of dopamine?

Answer 7

Ventral Tegmentum

Substantia Nigra pars compacta

Question 8

What amino acid is dopamine derived from?

Answer 8

Phenylalanine

Question 9

Where is the location of the ventral tegmentum?

Answer 9

Midbrain

Question 10

What are the projections of the reward system in the brain?

Answer 10

Projections from the Ventral Tegmentum to the Nucleus accumbens in the forebrain