Male Reproductive Physiology Flashcards

1
Q

What is contained in the seminiferous tubule?

A

Germ and Sertoli cells

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2
Q

What is the function of Sertoli cells?

A

Support the sperm-producing cells and produce inhibin

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3
Q

What do the interstitial cells of Leydig produce?

A

Testosterone

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4
Q

What is the difference between mitosis/meiosis in males and females?

A

Mitosis and meiosis in males continues throughout life and does not stop until puberty as it does in females

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5
Q

How many mature sperm cells are produced by one spermatogenesis cycle?

A

4

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6
Q

Where is GnRH released?

A

From the hypothalamus

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7
Q

Where are FSH and LH released?

A

From the pituitary

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8
Q

Where is testosterone released?

A

From the testes

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9
Q

What gives the first signal to the anterior pituitary to release gonadotrophins?

A

GnRH from the hypothalamus

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10
Q

What does FSH act on in males?

A

Sperm-producing cells - stimulates them to produce sperm

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11
Q

What does LH act on?

A

Interstitial cells of Leydig - stimulates them to produce testosterone
Sustentacular cells in the seminiferous tubules

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12
Q

What do androgens contribute to in males?

A

Secondary sex characteristics

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13
Q

What is the difference in positive feedback between males and females?

A

There is no positive feedback in males - sperm is continuously produced

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14
Q

What do Sertoli cells produce?

A

Inhibin

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15
Q

What act as negative feedback to the anterior pituitary to prevent excess sperm production?

A

Sertoli cells and testosterone

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16
Q

When is spermatogenesis onset?

A

At puberty

17
Q

How many days does a full cycle of production of sperm take?

A

60-75

18
Q

How many days does the transport of sperm to the epididymis take?

A

10-14

19
Q

How many sperm are present per ml of ejaculate?

A

15-100 million

20
Q

Where does sperm maturation occur?

A

Epididymis

21
Q

Why can an unhealthy lifestyle cause fertility problems?

A

Smoking/alcohol/drugs produces oxygen free radicals which negatively affect matured sperm

22
Q

How does sperm travel to the urethra?

A

Through the vas deferens

23
Q

What feature of sperm is designed to help burrow through the corona radiata and bona pellucida of the egg?

A

The acrosome

24
Q

How does the acrosome aid fertilisation?

A

Sperm cap releases enzymes from the acrosome which help it to reach the egg and release its genetic material for fertilisation

25
Q

What is the term for low sperm number?

A

Oligozoospermia

26
Q

What is the term for no sperm in the ejaculate?

A

Azoospermia

27
Q

What are the potential problems causing oligo/azoospermia?

A

Hormonal
Production
Transport

28
Q

What are some hormonal problems that can cause oligo/azoospermia?

A

Pituitary
Brain
Stress
Weight change

29
Q

What are some production problems that can cause oligo/azoospermia?

A

Testicular problems e.g. poorly formed, undescended, infection
Chemotherapy/radiotherapy