Male Pathophys 2 (Handorf) Flashcards
most common germ line cell tumor (in pure form)
seminoma
produces hCG
choriocarcinoma
produces AFP
yolk sac tumor
grossly homogenous looking testicular tumor
seminoma
tissue of tumor represents more than 1 germ layer
teratoma
fried egg appearence histo
seminoma
almost exclusively a germ cell tumor of infants and children up to 3 years
yolk sac (also produces AFP)
anaplastic looking cells under micro
embryonal carcinoma
mimics the histo of placenta
choriocarcinoma
germ line tumor that is characteristically necrotic and hemorrhagic? not necrotic or hemorragic?
embryonal carcinoma is hemorrhagic and necrotic
seminoma is not hemorrhagic or necrotic
Schiller–Duval body
yolk sac tumor characteristic histo finding
mets of this tumor bleed very easily bc it is a very vascular tumor
choriocarcinoma
cysts are common with what type of germ cell tumors?
teratomas
in what prostate zone does BPH arise?
central: transitional and periurethral zones
in what prostate zone does prostate cancer arise?
peripheral zone
what does the prostate produce
seminal fluid
what does the prostate encircle?
neck of the bladder
what type of epithelium does prostate have?
luminal and basal
what cells of the prostate express PSA
luminal epithelial cells
what is PSA
serine protease that liquifies seminal fluid coagulum
stains with P63
basal epithelial cells of the prostate
what are common causes of acute prostate inflammation?
E. coli, chlamydia, gonorrhea
what drives BPH
androgens
what cells are hyperplastic in BPH
prostatic glands and stroma
