Male infertility + ED Flashcards

1
Q

How long for changes in semen to be reflected after tratment?

A

74-76 day cycle + 12 day sperm travel ~ 3 months

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2
Q

Genetic causes of Impotence

A
  • Karyotypic: Klinefelters, Microdeletion on Y
  • Congenital absence of Vas Deferens: CF/CFTR gene; Wolfian duct anomaly
  • 46 XX Male Syndrome
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3
Q

Ejaculation reference Values

A
  • Volume: 1.5 - 5.0 ml
  • pH: > 7.2
  • Concentration > 20 mil/ml
  • motility > 50%
  • Normal Morph (Strict Kruger > 14%)
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4
Q

Hormonal Treatment of infertility in men

A
  • Low Test, High prolactin -> prolactinoma -> Bromocriptine
  • anti-estrogens: Clomiphene, Tamoxiphen
  • **Exogenous Androgenic steroids DEC LH + Testicular testosterone
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5
Q

Pt comes in with low sperm volume, painful ejac, acidic pH, and tests neg for fructose, Transrectal US reveals_______

A

Ejaculatory duct obstruction

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6
Q

ART

A

Assisted Reproductive Technology

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7
Q

ICSI

A

Intra‐Cytoplasmic Sperm Injection

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8
Q

IUI

A

Intra‐Uterine Insemination (Artificial Insemination)

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9
Q

GPD

A

Genetic Pre‐implantation Diagnosis

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10
Q

TESE

A

Testicular/Epididymal Sperm Extraction

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11
Q

Oligospermia
Azoospermia
Aesthenospermia
Teratospermia

A
  • Oligospermia‐Low Sperm Concentration
  • Azoospermia ‐NO Sperm seen
  • Aesthenospermi ‐Poor Motility
  • Teratospermia ‐Low Percentage of Normal Morphology
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12
Q

Neural Controls Erection/Ejaculation

A

PSNS S2-4 for erection

SNS T10-L2 for emission w/ some pudendal nerve involvement

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13
Q

Testosterone supplementation SE

A
  • Irritability
  • Liver Toxicity
  • Gynecomastia
  • Sleep apnea
  • BPH + Prostate Cancer
  • CV Dx
  • INC hematocrit
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14
Q

Priapism Tx

  • Usual
  • SCD
  • Other low Flow
  • High Flow
A
  • Usual: Stop sexual activity, sudafed, cold shower, + DEC stimulation
  • SCD: Analgesics, hydration, O2, + alkalinize
  • Other: Aspiration/irrigation w/ vasoconstrictors
  • High Flow: Embolization or Sx ligation
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15
Q

Medications A/S ED

A
  • Anti-HTN
  • Hormonal Agents
  • Cardiac Medication
  • H-2 Receptor antagonists
  • Psychoactives
  • Cytotoxic agents
  • Lipid-lowering
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16
Q

SHIM Questions

A
  • How do you rate you confidence to get and keep an erection?
  • When you had erections with sexual stimulation, how often were your erections hard enough for penetration?
  • During sexual intercourse, how often were you able to maintain erection after penetration?
  • During intercourse, how difficult was it to maintain your erection to completion?
  • When you attempted sexual intercourse, how often was it satisfactory for you?
17
Q

Erection molecule mediator + PDE-5

A

NO -> GC-> INC cGMP -> Erection

PDE5 breakds down cGMP,

18
Q

Contra for PGE5 inhibitors

A

Nitrates