Male and female repro histo Flashcards

(48 cards)

1
Q

ovarian epithelium? What is underneath?

A

simple (squamous or cubdoidal) 70% of ovarian tumours come from here. underneath is tunica albuginea (dense connective tissue).

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2
Q

how many oocytes in embryo and at birth?

A

5 mil.

0.5 mil

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3
Q

what is a PRIMORDIAL oocyte?

A

oocyte arrested in meoisis 1

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4
Q

what stage of meiosis are primordial oocytes arrested?

A

prophase

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5
Q

describe the cell progression as a primary oocyte mature

A

PO - the follicle cells become granulosa cells and form the stratum granulosum. The stromal cells becomes theca.
SF - as the stratum granulosum thickens, a fluid filled cavity (antrum) appears. Oocyte suspended on stalk of granulosa cells (cumulus oophorus).
SO - once follicle is mature LH surges causes completion of 1st meiotic division and follicle ruptures - releasing oocyte.

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6
Q

what is a graafian follicle?

A

mature follicle

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7
Q

how is the corpus luteum formed/

A

Once follicle loses oocyte, Stromal, granulosa and thecal cells invade cavity, differentiate into luteal cells.

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8
Q

what makes the corpus luteum yellow

A

lipid

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9
Q

what does corpus luteum do?

A

produce progesterone and estrogen to prepare endometrium

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10
Q

how does the oocyte move through the fallopian tube (2)?

A

epithelium is ciliated. peristalsis form smooth muscle

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11
Q

where does the oocyte get its nutrients whilst in fallopian tube?

A

fluid secreted by epithelium

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12
Q

what part of fallopian tube does fertilization usually occur?

A

ampulla

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13
Q

how is the uterine wall divided?

A

endometrium and myometrium

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14
Q

describe the myometrium of the uterus

A

3 layers of smooth muscle. inner and outer longitudinal and middle is circular.

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15
Q

how does the myometrium accommodate pregnancy at a cellular level.

A

enlarging individual smooth muscle cells, generating more smooth muscle cells and increasing connective tissue.

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16
Q

true or false, thickened uterine wall is retained after first pregnancy?

A

true

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17
Q

epithelium of endometrium

A

mix of ciliated and secretory simple columnar

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18
Q

describe the epithelium of cervix.

A

endocervix is simple columnar and glandular (secretes the vaginal discharge).
Ectocervix is stratified squamous (non glandular) to be a protective barrier.

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19
Q

describe the junction of the endo and ecto cervix

A

abrupt junction. Border changes depending on when in menstrual cycle and b/w reproductive and non-repro females. The stratified sheds cells

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20
Q

epithelium of vagina?

A

stratified squamous

21
Q

breast milk is high in which antibody?

22
Q

what is a mammary gland?

A

modified sweat gland that produces milk in postnatal mother.

23
Q

when do the mammary glands enlarge in the menstrual cycle? how?

A

during luteal phase. epithelial cells more columnar, some secretions (lumens appear), fluid accumulates in stroma connective tissue.

24
Q

what happens to mammary glands in pregnancy

A

Epithelial and myopeithelial cells proliferate from progenitor cells.
By term, have large cuboidal epithelial cells containing lipid and secretory product in lumen.

25
describe the structure of the testes from outside to in
tunica vaginalis > tunica albuginea > seminiferous tubules > rete testes > efferent ductules > head of epididymis > body > tail > vas deferens
26
epithelium of Seminiferous?
stratified squamous
27
what 2 cells of significance in tunica (lamina) propria of Seminiferous?
myoid (smooth muscle contractile) and Leydig (
28
support cells for spermatogenisis
Sertoli
29
how does sprem move down Seminiferous?
Tunica propria can contract to provide peristaltic movement
30
what do leydig cells do?
produce testosterone
31
Describe The final part of the seminiferous tubule (histologically). what are they called?
the Tubuli Recti is straight and lined with Sertoli cells only and finally simple cuboidal epithelium. connect to the rete testis
32
describe rete testis
an interconnected set of channels at the end of the seminiferous tubules. lined with ciliated cuboidal cells
33
from where is the epididymus derived?
mesonephric duct
34
what are the efferent ductules? where do they come from
connect rete testis to head of epididymus. they are Around 20 surviving mesonephric tubules
35
epithelium of efferent ductules?
pseudostratified ciliated columnar
36
function of epididymus? give an example
sperm mature as they move along. decapacitation, the inhibition of the ability of the sperm to fertilise an egg (reversed in vagina).
37
epi of vas deferens?
pseudostratified ciliated columnar
38
other name for vas deferns
ductus deferens
39
role of seminal vesicle
secrete fructose for energy. make sperm alkaline
40
where is prostate anatomically?
anterior rectum wall, inferior to bladder.
41
describe openings of prostate
central urethra, inferior paired ejaculatory duct, prostate sinuses
42
4 zones of prostate?
central, peripheral, transitional and periurethral
43
epithelium of prostate?
heterogenous (columnar or cuboidal, pseudostratified)
44
what is a prostatic concretion?
accumulation of protein, calcium-phosphate, cholesterol and cellular debris within lu2men. more common with age
45
secretion of prostate? give one example
complex. Initially causes the ejaculate to clot (immobilising it) but then fibrolysin dissolves clot and frees sperm to move
46
3 masses of erectile tissue in penis. where is urethra
2 x corpus cavanosa and 1 x corpus spongiosum. urethra in c. spongiosum
47
where does Crus of clitoris extends?
inferiorly along pelvis
48
Role of the bulbs of clitoris?
unknown - no male homologue