Malaria Flashcards
1
Q
Benign Organisms
A
- P Vivax
- P Ovale
- P malariae
2
Q
Malignant organisms
A
P falciparum
3
Q
Transmission
A
By the bite of the female anopheline mosquito
4
Q
Life cycle
A
- during blood emal, female inocluates sporozites into human host
- sporozites infect liver cells and mature into schiznots which rupture and release merozited
- can remain dormant in liver cells
- asexual multiplication in erythrocytes
5
Q
Clinical features
A
classical cyclical (cold, hot stage, sweats)
- rigors
- headache
- myalgia
- diarrhoea and vomitting
6
Q
Treatment of benign malaria
A
not life threatening and is treated as outpatients with chloroquine for 3 days followed by primaquine for two weeks (to eradicate liver cells)
7
Q
Diagnosis
A
- what type ? - thin film
- thick film - most sensitive, requires expertise
- rapid antigen test
- Blood cultures
- PCR
- urine and stool cultures
- HIV test
8
Q
Treatment of P falciparum
A
- oral or intravenous quinine
9
Q
Complications of falicparum malaria
A
- cerebral malaria
- haemolytic anaemia
- metabolic acidsis
- hypoglycaemia
- acute renal failure
- pulmonary oedema
