Malaria Flashcards
name that drugs used as prophylaxis for Malaria
- doxycycline
- mefloquine
- Atovaquone-proguanil
give examples of doxycyclines
- Doxymal
- Doxytab
- Doxycycline
- Cyclidox
give examples of mefloquine
- Lariam
- Mafliam
give examples of Atovaquone-Proguanil
- Malanil
- Malateq
- Mozitec
how frequent do you take the malaria propylaxis drugs
- AP and doxycycline are taken daily
- mefloquien is taken weekly
when should you start taking the drugs initially
AP and doxycyline are taken 1 to 2 days before eteh trip while mefloquine is taken 1 to 2 weeks before the trip
after how long post the trip should you still take the medication
- 7 days with AP
- 4 WEEKS with mefloquine and doxycycline
which of the drugs can be used in pregnancy
ONLY mefloquine
when can a drug be used for children
- mefloquine: a child that is over 5kg
- AP: a child that is over 11kg
- Doxycycline: a child that is over teh age of 8.
which drug is the safest in HIV+ patients and what is the clinical implication of the other drugs
- ONLY Doxycycline can be used for HIV+ patients, the other drugs have the potential of Drug interaction and this makes not not to be the safest.
implications of drugs in epilepsy
- AP: can be used
- Doxycycline: can be used BUT has some drug interactions
- Mefloquine: contraindicated
which drug cannot be used for psychiatric conditions
Mefloquine, even if its based only on history and not official diagnosis
which drug is the safest in renal/hepatic impairement
- Doxycycline is the safest.
- mefloquine is contraindicated in hepatoc impairement
- AP is contraindicated in renal impairement with a GFR less than 30
which drug has contraindication in diabetes and why
Doxycycline, it increases insulin related hypoglycaemia.
other drugs safe to use.
what precautions must one take when taking doxycycline
- must apply sun screen
- take a full glass of water
- should not lie down one after after dose
