ASTHMA AND COPD Flashcards
relivers
Name the short acting beta 2 agonots
- salbutamol
- fenoterol
- terbutaline
are anti cholinegics relivers or controllers
reliever
give an example of an anticholinergic
ipratropium bromide
name the long acting beta 2 agonits
- salbutamol
- formeterol
what does theophylline do
it provides sustained brochodilatin but has weak or unproven anti inflammatory effects
name 4 inhaled corticosteriods
- Beclomethasone
- Budesonide
- Fluticasone
- Circlesonide
give names of leukotriene modifiers
- Montelukast
- Zafirlurkast
names of oral corticosteriods
- prednisone
- prinisolone
- Methylprednisone
- Methylprenisolone
what is the starting dose of beclomethasone
200mcg 12 hourly
what dose of beclomethasone do you increase to if teh starting dose does not work
400mcg 12 hourly
whats the second line of treatment for asthma
salbutamol and fluticasone
50/250 1 puff 12 hourly
what is the drug of choice for relief of bronchospasm during acute exacebation
- short acting beta 2 agonits, given using a metered dose inhaler with spacer or nebuliser.
which class of drugs is ipratroprium bromide
- it is a anticholinergic
- it inhibits bronchostriction
- it can be used as an additive effect with beta agonits.
what do inhaled corticosteriods do
they bind to glucocorticoid recotor and alter gene expression and bring about anti inflammatory action.
most effective anti-inflammatory
what is the mode of action of long acting beta 2 agonists
they bind to beta 2 receptors and stimulate adenylyl cyclase and this will increase cAMP and cause bronchodilation.
