Malabsorptive & Diarrheal diseases Flashcards
celiac diisease
Terminal digestion
Transepithelial transport
tropical sprue
Terminal digestion
Transepithelial transport
chronic pancreatitis
Intraluminal digestion
cystic fibrosis
Intraluminal digestion
autoimmue enteropathy
Terminal digestion
Transepithelial transport
Disaccharidase deficiency
Terminal digestion (only pure)
Whipple disease
Lymphatic transport (only pure)
- FARMERS
- arthritis
- fever, anemia, endocarditis, CNS disease, other
-PAS positive macrophages in lamina propria of SI w/ rod-shaped bacgeria
Abetalipoproteinemia
Transepithelial transport (only pure)
- mutated microsomal triglyceride transfer protein
- lipid vacuoles in cytoplasm of enterocytes
- acanthocytes - hemolytic anemia
Viral/Bacterial/Parasitic gastroenteritis
Terminal digestion
Transepithelial transport
Inflammatory Bowel Disease
Intraluminal digestion
Terminal digestion
Transepithelial transport
Norovirus
Rotavirus
Adenovirus
Acute watery diarrhea
- villous shortening; loss of brush border
- mature enterocyte apoptosis; replaced by immature that cannot do terminal digestion and absorption
- villous atrophy w/ viral nuclear inclusions
causes of bloody stool
Esophagus/Stomach
- Mallory-Weiss tear
- esophageal varices
- gastric/duodenal ulcers
- hemorrhagic gastritis
Small intestine:
- Ischemic bowel disease
- Intussusception
- Meckel diverticulum
Colon:
- angiodysplasia (right)
- colonic carcinoma
- bacterial infections that cause ulcerations
- Inflammatory bowel disease (Crohns and UC)
- Diverticulopsus
- Hemorrhoids
- Anal fissure
