Magnesium Flashcards
Where is magnesium digested and absorbed
jejunum and ileum
How is Mg absorbed
low conc: carrier mediated system
high conc: simple
30-60%
What enhances bioavailability
vit D
What inhibits bioavailability
phytates, fiber, unabs, fat
How is Mg transported
1/2 free ionic state, 1/3 bound to albumin, rest part of various compunds
How is Mg excreted
kidneys maintain homeostasis, unabsorbed Mg through fecal excretion, small amounts in sweat
What are the metabolic roles of Mg
1) cofactor for enzymes (ATPases and phosphorylations)
2) primary divalent intracellular cation in tissues
3)extracellular needed for neuronmusclular function
4) Ca and K metabolism
Is primary or secondary deficiency more common
secondary; seen in alcholics, severe diarrhea, excess Ca intake, renal disease
DRI/RDA
310mg/day women
400mg/d male
Signs of deficiency
nausea, vomiting, muscle issues, nervous system changes, low blood Ca
UL
350mg from SUPPLEMENTAL Mg
Toxicity
not likely; caused by impaired renal function
Food sources of Mg
chlorophyll, green leafy vegetables, unrefined grains, nuts