Antioxidants Flashcards
Superoxide Radical
O2-
Creation of superoxide radical
O2 + e- = O2-
Where des the electron need to create the superoxide radical come from
leaking of electrons from ETC onto oxygen
How is O2- eliminated
Ascorbic acid (AH2) or SOD (superoxide dismuatse)
What are SOD’s cofactors
Zn-Cu (outside of mito) or Mn (inside mito)
Hydrogen Peroxide
H2O2 (not stable)
How is H2O2 formed
O2- +O2- +2H+ = H2O2 + O2
How is H2O2 eliminated
ascorbic acid or Glutathionine Peroxidase (GPx) or catalase
What is GPx dependent on
selenium
Hydroxyl Radical
OH* (strong radical)
How is OH* formed
(H2O2 + O2- + H+ = H2O +O2+ OH) OR (Fe+2 + H2O2 = Fe+3 +OH + OH-
what will a reduced form of iron cause
rust, hydroxyl, hydroxyl radical
How is OH* eliminated
ascorbic acid and GPx
3 types of lipid radicals
radicals, peroxyl radicals, peroxides
Lipid radical
L-