Antioxidants Flashcards

1
Q

Superoxide Radical

A

O2-

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2
Q

Creation of superoxide radical

A

O2 + e- = O2-

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3
Q

Where des the electron need to create the superoxide radical come from

A

leaking of electrons from ETC onto oxygen

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4
Q

How is O2- eliminated

A

Ascorbic acid (AH2) or SOD (superoxide dismuatse)

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5
Q

What are SOD’s cofactors

A

Zn-Cu (outside of mito) or Mn (inside mito)

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6
Q

Hydrogen Peroxide

A

H2O2 (not stable)

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7
Q

How is H2O2 formed

A

O2- +O2- +2H+ = H2O2 + O2

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8
Q

How is H2O2 eliminated

A

ascorbic acid or Glutathionine Peroxidase (GPx) or catalase

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9
Q

What is GPx dependent on

A

selenium

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10
Q

Hydroxyl Radical

A

OH* (strong radical)

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11
Q

How is OH* formed

A

(H2O2 + O2- + H+ = H2O +O2+ OH) OR (Fe+2 + H2O2 = Fe+3 +OH + OH-

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12
Q

what will a reduced form of iron cause

A

rust, hydroxyl, hydroxyl radical

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13
Q

How is OH* eliminated

A

ascorbic acid and GPx

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14
Q

3 types of lipid radicals

A

radicals, peroxyl radicals, peroxides

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15
Q

Lipid radical

A

L-

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16
Q

Lipid Peroxyl Radicals

A

LOO-

17
Q

Lipid Peroxides

A

L- + LOOH

18
Q

How is lipid radical eliminated

A

Vitamin E

19
Q

How are lipid peroxyl radicals eliminated

A

Vitamin E

20
Q

How are lipid peroxides eliminated

A

GPx