MACROLIDES (MYCIN) Flashcards

1
Q

Mechanism of Action

A

Bacteriostatic but can be bactericidal in high concentrations

Effective against a broad range of infections such as RI and skin/soft tissue infections

Syphilis, Lyme disease, Chlamydia

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2
Q

Indications

A

RI

Spirochetal infections (syphilis, Lyme)

STDs (gonorrhea, chlamydia)

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3
Q

Contraindications

A

Known drug allergy

Used as an alternative for β-lactam antibiotic allergies

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4
Q

Adverse Effects

A

GI related adverse effects (nausea, vomiting, constipation)

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5
Q

Interactions

A

Oral contraceptives

Cytochrome P450

Simvastatin/Lovastatin

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6
Q

Nursing Considerations/Patient Teaching

A

Cannot be given with fruit juices

Usually taken with food

Will cause severe interactions with other protein-bound drugs

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