CARBAPENEMS (β-Lactam) Flashcards

1
Q

Mechanism of Action

A

Bactericidal

Inhibits bacterial cell wall synthesis

Broadest antibacterial action

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2
Q

Indications

A

Effective against many gram+ and gram- organisms

Used in severe, complicated infections when other antibiotics are ineffective

Severe skin infections, pneumonia, intra-abdominal infections

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3
Q

Adverse Effects

A

Risk for seizures

Cross-sensitivity with penicillin allergy

GI disturbances, allergic reactions

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4
Q

Nursing Considerations/Patient Teaching

A

Must be infused over 60 minutes to avoid adverse effects

Dosage adjustment required for patients with renal impairment

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