macrolides Flashcards
1
Q
examples of macrocodes
A
erythromycin, clarythromycin and azithromycin
2
Q
the macrocodes are excreted
A
via the liver, biliary tract and the gut and NOT via the kidneys
3
Q
macrocodes are
A
lipophilic so they pass through cell membranes very easily so are useful for treating infections where bacteria hide from the hosts immune system by getting into host cells (legionella) and bacteria that do not have a proper bacterial cell wall (mycoplasma and chlamydia)
4
Q
are macrocodes safe to use in pregnancy
A
erythromycin is safe to use in pregnancy but clarythromycin and azithromycin have not been trialled
