cephalosporins Flashcards
1
Q
mechanism of action
A
inhibits cell wall synthesis by preventing peptidoglycan cross linking therefore is bactericidal
2
Q
cephalosporins are excreted
A
via the kidneys
3
Q
are cephalosporins safe in pregnancy
A
yes
4
Q
cephalosporins are very
A
broad spectrum antibiotics which kill of the normal gut flora allowing the overgrowth of C. difficile so use is very controlled
5
Q
each successive generation of cephalosporins is
A
more broad than the previous
6
Q
1st generation cephalosporins
A
cefalex
7
Q
2nd generation cephalosporins
A
cefuroxime
8
Q
3rd generation cephalosporins
A
cefixime (gonorrhoea)
ceftriaxone (meningitis and acute epiglottis)
ceftazimide (active against pseudomonas)
